Results 21 to 30 of about 2,517,057 (344)
Signal Transduction and Targeted Therapy, 2021 SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and model animals. However, it remains unclear whether and how SARS-CoV-2 crosses the blood–brain barrier (BBB).
Ling Zhang +20 more
semanticscholar +1 more source
Mechanisms of Basement Membrane Micro-Perforation during Cancer Cell Invasion into a 3D Collagen Gel
Gels, 2022 Cancer invasion through basement membranes represents the initial step of tumor dissemination and metastasis. However, little is known about how human cancer cells breach basement membranes.
Shayan S. Nazari +2 more
doaj +1 more source
Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
doaj +1 more source
Journal of clinical pathology. Supplement, 2020 Ubiquitous supportive tissue adjacent to epithelium and around smooth and striated muscle cells. This tissue contains intrinsic macromolecular components such as collagen, laminin, and sulfated proteoglycans.
J. Ireland
openaire +2 more sources
Long Prehensile Protrusions Can Facilitate Cancer Cell Invasion through the Basement Membrane
Cells, 2023 A basic process in cancer is the breaching of basement-membrane barriers to permit tissue invasion. Cancer cells can use proteases and physical mechanisms to produce initial holes in basement membranes, but how cells squeeze through this barrier into ...
Shayan S. Nazari +3 more
doaj +1 more source
The prognostic significance of type IV collagen expression in colorectal carcinomas [PDF]
Archive of Oncology, 2003 BACKGROUND: Breakdown of basement membrane is believed to be an essential step for tumor invasion and metastasis. The interaction between tumor cells and extracellular matrix can also result in induction of basement membrane synthesis by tumor and ...
Fenyvesi Attila
doaj +1 more source
Current Biology, 2017 Basement membranes (BMs) are thin, dense sheets of specialized, self-assembled extracellular matrix that surround most animal tissues (Figure 1, top). The emergence of BMs coincided with the origin of multicellularity in animals, suggesting that they were essential for the formation of tissues.
Ranjay, Jayadev, David R, Sherwood
openaire +2 more sources
Anti-Glomerular Basement Membrane Disease
Definitions, 2020 Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement ...
A. Rees
semanticscholar +1 more source
Anti-Glomerular Basement Membrane Disease in a 10-year-old Child: A Case Report
Journal of Nepal Medical Association, 2023 Anti-glomerular basement membrane disease is an extremely uncommon entity in children. It has an incidence of 0.5 to 1 per million per year in adults and is even more uncommon in children.
Md Firoz Anjum +4 more
doaj +1 more source
Basement membrane components [PDF]
Journal of Clinical Pathology, 2003 New blood tests in inflammatory bowel disease Idiopathic inflammatory bowel disease (IBD) collectively describes ulcerative colitis (UC) and Crohn’s disease (CD). UC is characterised by inflammation limited to the colonic mucosa and collagen deposition only in the submucosa,1 whereas CD is characterised by transmural, granulomatous inflammation and ...
A C Y, Li, R P H, Thompson
openaire +2 more sources