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The prognostic significance of type IV collagen expression in colorectal carcinomas [PDF]
BACKGROUND: Breakdown of basement membrane is believed to be an essential step for tumor invasion and metastasis. The interaction between tumor cells and extracellular matrix can also result in induction of basement membrane synthesis by tumor and ...
Fenyvesi Attila
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Basement membranes (BMs) are thin, dense sheets of specialized, self-assembled extracellular matrix that surround most animal tissues (Figure 1, top). The emergence of BMs coincided with the origin of multicellularity in animals, suggesting that they were essential for the formation of tissues.
Ranjay, Jayadev, David R, Sherwood
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Basement membrane components [PDF]
New blood tests in inflammatory bowel disease Idiopathic inflammatory bowel disease (IBD) collectively describes ulcerative colitis (UC) and Crohn’s disease (CD). UC is characterised by inflammation limited to the colonic mucosa and collagen deposition only in the submucosa,1 whereas CD is characterised by transmural, granulomatous inflammation and ...
A C Y, Li, R P H, Thompson
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Antiglomerular Basement Membrane Disease [PDF]
AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
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Anti-Glomerular Basement Membrane Disease in a 10-year-old Child: A Case Report
Anti-glomerular basement membrane disease is an extremely uncommon entity in children. It has an incidence of 0.5 to 1 per million per year in adults and is even more uncommon in children.
Md Firoz Anjum +4 more
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The differentiation of human stem cells into insulin secreting beta‐like cells holds great promise to treat diabetes. Current protocols drive stem cells through stages of directed differentiation and maturation and produce cells that secrete insulin in ...
Reena Singh +7 more
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Advances in the effect of NC1 domain of type Ⅳ collagen on spermatogenesis and blood-testis barrier [PDF]
In mammalian testis, the blood-testis barrier (BTB), located near the basement membrane of seminiferous epithelium, is essential for spermatogenesis.
JIANG Shuyi, SU Wenhui
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The time-dependent rearrangement of the epithelial basement membrane in human skin wounds [PDF]
In 62 human skin wounds (surgical wounds, stab wounds and lacerations after surgical treatment) we analyzed the immunohistochemical localization of collagen IV in the epithelial basement membrane.
A Martinez-Hernandez +26 more
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Basement membranes are thin, specialized extracellular matrices surrounding most tissues in all metazoans. The compositions and functions of basement membranes have generally been well conserved throughout the subkingdom. Genetic analyses of basement membrane components in C.
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Genetic Suppression of Basement Membrane Defects in Caenorhabditis elegans by Gain of Function in Extracellular Matrix and Cell-Matrix Attachment Genes. [PDF]
Basement membranes are extracellular matrices essential for embryonic development in animals. Peroxidasins are extracellular peroxidases implicated in the unique sulfilimine cross-links between type IV basement membrane collagens. Loss of function in the
Chisholm, Andrew D +3 more
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