The Acinar Cage: Basement Membranes Determine Molecule Exchange and Mechanical Stability of Human Breast Cell Acini. [PDF]
PLoS ONE, 2015 The biophysical properties of the basement membrane that surrounds human breast glands are poorly understood, but are thought to be decisive for normal organ function and malignancy.
Aljona Gaiko-Shcherbak +5 more
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Anti-glomerular basement membrane disease superimposed on membranous nephropathy: a case report and review of the literature [PDF]
Journal of Medical Case Reports, 2010 Introduction Anti-glomerular basement membrane disease is a rare autoimmune disorder characterized by pulmonary hemorrhage, crescentic glomerulonephritis and the presence of circulating anti-glomerular basement membrane antibodies.
Nivera Noel +2 more
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Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries. [PDF]
PLoS ONE, 2012 The labyrinth is the highly vascularized part of the rodent placenta that allows efficient transfer of gases, nutrients, wastes, and other molecules between the maternal and embryonic circulations. These two blood compartments are separated by blastocyst-
Sung Tae Kim +3 more
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Basement membrane perforations guide anterior–posterior axis formation [PDF]
Nature CommunicationsEstablishment of the anterior-posterior (AP) axis is a critical symmetry-breaking event in mammalian development. In mice, this process involves the directed migration of the distal visceral endoderm (DVE).
Dong-Yuan Chen +9 more
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Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases [PDF]
European Respiratory ReviewChronic lung diseases such as COPD, asthma, idiopathic pulmonary fibrosis (IPF) and pulmonary hypertension are characterised by aberrant remodelling and degradation of the extracellular matrix.
Natalia El-Merhie +3 more
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Vascular Basement Membrane Fragmentation in Keloids and the Expression of Key Basement Membrane Component Genes [PDF]
Plastic and Reconstructive Surgery, Global OpenBackground:. Keloids are growing scars that arise from injury to the reticular dermis and subsequent chronic local inflammation. The latter may be promoted by vascular hyperpermeability, which permits the ingress of chronic inflammatory cells/factors ...
Yusaku Saijo, MD +3 more
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To form and function: on the role of basement membrane mechanics in tissue development, homeostasis and disease [PDF]
Open Biology, 2021 The basement membrane (BM) is a special type of extracellular matrix that lines the basal side of epithelial and endothelial tissues. Functionally, the BM is important for providing physical and biochemical cues to the overlying cells, sculpting the ...
Nargess Khalilgharibi, Yanlan Mao
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Mechanisms of Basement Membrane Micro-Perforation during Cancer Cell Invasion into a 3D Collagen Gel
Gels, 2022 Cancer invasion through basement membranes represents the initial step of tumor dissemination and metastasis. However, little is known about how human cancer cells breach basement membranes.
Shayan S. Nazari +2 more
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Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
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Long Prehensile Protrusions Can Facilitate Cancer Cell Invasion through the Basement Membrane
Cells, 2023 A basic process in cancer is the breaching of basement-membrane barriers to permit tissue invasion. Cancer cells can use proteases and physical mechanisms to produce initial holes in basement membranes, but how cells squeeze through this barrier into ...
Shayan S. Nazari +3 more
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