Results 51 to 60 of about 2,517,057 (344)

The glomerular basement membrane [PDF]

Experimental Cell Research, 2012
The kidney's glomerular filtration barrier consists of two cells-podocytes and endothelial cells-and the glomerular basement membrane (GBM), a specialized extracellular matrix that lies between them. Like all basement membranes, the GBM consists mainly of laminin, type IV collagen, nidogen, and heparan sulfate proteoglycan.
openaire   +2 more sources

Anti-glomerular basement membrane disease superimposed on membranous nephropathy: a case report and review of the literature

Journal of Medical Case Reports, 2010
Introduction Anti-glomerular basement membrane disease is a rare autoimmune disorder characterized by pulmonary hemorrhage, crescentic glomerulonephritis and the presence of circulating anti-glomerular basement membrane antibodies.
Nivera Noel, Patel Dhruval, Tunkel Allan R   +2 more
doaj   +1 more source

Basement membrane and cell integrity of self-tissues in maintaining Drosophila immunological tolerance. [PDF]

PLoS Genetics, 2014
The mechanism underlying immune system recognition of different types of pathogens has been extensively studied over the past few decades; however, the mechanism by which healthy self-tissue evades an attack by its own immune system is less well ...
Moon Jong Kim, Kwang-Min Choe
doaj   +1 more source

Vasa Vasorum in Saphenous Vein for CABG: A Review of Morphological Characteristics

Brazilian Journal of Cardiovascular Surgery, 2023
This short article discusses selected scanning electron microscope and transmission electron microscope features of vasa vasorum including pericytes and basement membrane of the human saphenous vein (SV) harvested with either conventional (CON) or no ...
Andrzej Loesch
doaj   +1 more source

Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]

, 2015
20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
Calvete, JJ, Rucavado Romero, Alexandra, Rucavado, A, Cristina Herrera (576490), Jéssica Kele A. Macêdo (729670), Morazan, D, Diego Morazán (729669), Mathieu-Benoit Voisin (729668), Escalante, Teresa, Libia Sanz, Mathieu-Benoit Voisin, Alexandra Rucavado (32147), Herrera, C, Macêdo, Jéssica Kele A., Jéssica Kele A Macêdo, Teresa Escalante, Calvete Chornet, Juan José, Nourshargh, S, Diego Morazán, Cristina Herrera, Voisin, Mathieu-Benoit, Voisin, M-B, Maria Gutierrez, J, Rucavado, Alexandra, Jay W Fox, José María Gutiérrez, Alexandra Rucavado, Macedo, JKA, Libia Sanz (144843), Juan J. Calvete (144840), Sanz, L, Juan J Calvete, Sussan Nourshargh (157725), Sanz, Libia, Morazán, Diego, Nourshargh, Sussan, Jay W. Fox (164576), Escalante, T, Teresa Escalante (337914), Herrera, Cristina, Calvete, Juan J., Sussan Nourshargh, José María Gutiérrez (62868), Escalante Muñoz, Teresa, Herrera Arias, Cristina, Fox, JW, Fox, Jay W., Gutiérrez, José María   +47 more
core   +1 more source

Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane

Nature Communications, 2017
At the stage of carcinoma in situ, the basement membrane (BM) segregates tumor cells from the stroma. This barrier must be breached to allow dissemination of the tumor cells to adjacent tissues.
Alexandros Glentis, P. Oertle, P. Mariani, A. Chikina, F. El Marjou, Youmna Attieh, Francois Zaccarini, M. Laé, D. Loew, F. Dingli, P. Sirven, Marie Schoumacher, Basile G. Gurchenkov, M. Plodinec, D. Vignjevic   +14 more
semanticscholar   +1 more source

Molecular composition of the peri-islet basement membrane in NOD mice: a barrier against destructive insulitis [PDF]

, 2008
Aims/hypothesisThis study examined whether the capsule which encases islets of Langerhans in the NOD mouse pancreas represents a specialised extracellular matrix (ECM) or basement membrane that protects islets from autoimmune attack ...
Rodgers, R., Irving-Rodgers, H., Rodgers, Raymond, Irving-Rodgers, Helen, Sado, Yoshikazu, Ziolkowski, A., Ziolkowski, Andrew, H. F. Irving-Rodgers, C. J. Simeonovic, R. J. Rodgers, Rodgers, Ray, Sado, Y., Parish, Christopher, Ninomiya, Yoshifumi, C. R. Parish, Simeonovic, C., Ninomiya, Y., Y. Sado, A. F. Ziolkowski, Y. Ninomiya, Simeonovic, Charmaine, Parish, C., Irving-Rodgers, H.F.   +22 more
core   +1 more source

Basement membrane collagens and disease mechanisms

Essays in Biochemistry, 2019
Basement membranes (BMs) are specialised extracellular matrix (ECM) structures and collagens are a key component required for BM function. While collagen IV is the major BM collagen, collagens VI, VII, XV, XVII and XVIII are also present.
Anna Gatseva, Yuan Yan Sin, G. Brezzo, T. Van Agtmael   +3 more
semanticscholar   +1 more source

Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways

Acta Neuropathologica, 2018
Tracers injected into CSF pass into the brain alongside arteries and out again. This has been recently termed the “glymphatic system” that proposes tracers enter the brain along periarterial “spaces” and leave the brain along the walls of veins.
Nazira J. Albargothy, D. Johnston, Matthew T. MacGregor‐Sharp, R. Weller, A. Verma, C. Hawkes, R. Carare   +6 more
semanticscholar   +1 more source

Molecular and Cellular Mechanisms Underlying the Initiation and Progression of Alport Glomerular Pathology

Frontiers in Medicine, 2022
Alport syndrome results from a myriad of variants in the COL4A3, COL4A4, or COL4A5 genes that encode type IV (basement membrane) collagens. Unlike type IV collagen α1(IV)2α2(IV)1 heterotrimers, which are ubiquitous in basement membranes, α3/α4/α5 have a ...
Dominic Cosgrove, Jacob Madison
doaj   +1 more source