Results 51 to 60 of about 152,808 (261)

Association between matrix metalloproteinases-2 and -9 gene polymorphism with basement membrane disruption in oral lichen planus: A case-control pilot study

open access: yesJournal of Oral Biology and Craniofacial Research, 2022
Objectives: This study investigated genetic polymorphism of matrix metalloproteinases (MMP) −2 and −9 in oral lichen planus (OLP) and their association with the basement membrane status.
Anubhuti Sood   +4 more
doaj   +1 more source

Structure and Function of Basement Membrane.

open access: yesJournal of Investigative Dermatology, 1982
Progress has been made in identifying and characterizing basement membrane macromolecules, including type IV collagen, laminin, a heparan sulfate proteoglycan and bullous pemphigoid antigen. Basement membrane contains a unique collagen, type IV collagen, which is formed of pro alpha 1(IV) (Mr = 185,000) and pro alpha 2(IV) (Mr = 170,000) chains.
Stanley, John R.   +3 more
openaire   +2 more sources

Hierarchical Collagen Nanofiber Gels Recapitulate a Physiologically Relevant Tumor Stromal Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
The collagen nanofiber (CNF) gel supports cancer cell culture, exhibiting cell morphology and cancer‐related protein expression similar to Matrigel. It offers a higher collagen concentration than commercial gels. Additionally, the CNF gel allows replication of the high elasticity of in vivo cancer tissue by controlling collagen fiber sizes, ranging ...
Naoko Sasaki   +4 more
wiley   +1 more source

Nanofiber‐Supported Decellularized Matrix Membrane Creates a Biomimetic Biochemical and Biophysical Niche for Intestinal Organoid Epithelium

open access: yesAdvanced Healthcare Materials, EarlyView.
A nanofiber‐supported decellularized extracellular matrix (NaDE) membrane recreates key biochemical and mechanical features of native intestinal tissue. This platform enables the formation of a more physiologically relevant intestinal epithelium, enhancing stem cell maintenance and promoting diverse cell differentiation.
Jaeseung Youn   +7 more
wiley   +1 more source

Development of an in vitro platform for epithelial-stromal interactions: A basement membrane-containing scaffold from decellularized porcine bladders

open access: yesMatrix Biology Plus
The first organized extracellular matrix that appears during mammalian embryogenesis is a basement membrane (BM), BM is present in all adult epithelia, endothelia, muscle, nerve and fat tissues.
J.A. Ramirez   +3 more
doaj   +1 more source

Expression of basement membrane laminin in oral squamous cell carcinomas

open access: yesBrazilian Journal of Otorhinolaryngology, 2007
Summary: The basement membrane is a dynamic structure that undergoes quantitative and qualitative changes during the progression of squamous cell carcinoma, which is essencially important in tumoral invasion and metastasis.
Silvia Regina de Almeida Reis   +4 more
doaj   +1 more source

Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries. [PDF]

open access: yesPLoS ONE, 2012
The labyrinth is the highly vascularized part of the rodent placenta that allows efficient transfer of gases, nutrients, wastes, and other molecules between the maternal and embryonic circulations. These two blood compartments are separated by blastocyst-
Sung Tae Kim   +3 more
doaj   +1 more source

Basement membrane proteins

open access: yesKidney International, 1992
Basement membranes are heterogeneous, highly specialized, electron-dense structures constructed from components of extracellular matrix proteins 20 to 200nm in width. They provide anchorage for adjacent cells as well as stimuli for cell differentiation, cell migration, and cell phenotype.
openaire   +2 more sources

A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang   +16 more
wiley   +1 more source

Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases

open access: yesEuropean Respiratory Review
Chronic lung diseases such as COPD, asthma, idiopathic pulmonary fibrosis (IPF) and pulmonary hypertension are characterised by aberrant remodelling and degradation of the extracellular matrix.
Natalia El-Merhie   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy