Results 71 to 80 of about 257,213 (299)

IgG subclass deposition in diabetic nephropathy

European Journal of Medical Research, 2022
Purpose This study aimed to analyze the distribution of IgG subclass in diabetic nephropathy (DN) and its association with clinicopathological features.
Xuanli Tang, Feng Wan, Qin Zhu, Tian Ye, Xue Jiang, Haichun Yang   +5 more
doaj   +1 more source

Association between matrix metalloproteinases-2 and -9 gene polymorphism with basement membrane disruption in oral lichen planus: A case-control pilot study

Journal of Oral Biology and Craniofacial Research, 2022
Objectives: This study investigated genetic polymorphism of matrix metalloproteinases (MMP) −2 and −9 in oral lichen planus (OLP) and their association with the basement membrane status.
Anubhuti Sood, Latha Mary Cherian, R. Heera, Sanish Sathyan, Moinak Banerjee   +4 more
doaj   +1 more source

Diabetic Glomerulosclerosis [PDF]

, 1966
Why should the mesangial cells be irritated? We recently observed in some diabetics black deposits beneath and on both sides of the basement membrane. These appear quite similar to deposits seen in and around the basement membrane in glomerulonephritis ...
Bloodworth, J. M. B., Jr.
core   +1 more source

Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis [PDF]

, 2013
Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. The interaction of TG2 with the heparan sulfate proteoglycan syndecan-4 (Sdc4) regulates the cell surface trafficking, localization, and ...
Burhan, I, Funck, M, Huang, L, Johnson, TS, Scarpellini, A, Schroeder, N, Verderio, EAM   +6 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Correlated alterations in prostate basal cell layer and basement membrane

International Journal of Biological Sciences, 2009
Our recent studies revealed that focal basal cell layer disruption (FBCLD) induced auto-immunoreactions represented a contributing factor for human prostate tumor progression and invasion. As the basement membrane surrounds and attaches to the basal cell
Aijun Liu, Lixin Wei, William A. Gardner, Chu-Xia Deng, Yan-Gao Man
doaj  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Development of an in vitro platform for epithelial-stromal interactions: A basement membrane-containing scaffold from decellularized porcine bladders

Matrix Biology Plus
The first organized extracellular matrix that appears during mammalian embryogenesis is a basement membrane (BM), BM is present in all adult epithelia, endothelia, muscle, nerve and fat tissues.
J.A. Ramirez, S. Estrada, M.C. Harmsen, P.K. Sharma   +3 more
doaj   +1 more source

Expression of basement membrane laminin in oral squamous cell carcinomas

Brazilian Journal of Otorhinolaryngology, 2007
Summary: The basement membrane is a dynamic structure that undergoes quantitative and qualitative changes during the progression of squamous cell carcinoma, which is essencially important in tumoral invasion and metastasis.
Silvia Regina de Almeida Reis, Leonardo Francisco Provedel de Souza, Verônica Ferreira de Souza, Lílian Dantas de Góes Silva, Jean Nunes dos Santos   +4 more
doaj   +1 more source

Molecular mechanisms separating two axonal pathways during embryonic development of the avian optic tectum [PDF]

, 1991
During embryonic development of the avian optic tectum, retinal and tectobulbar axons form an orthogonal array of nerve processes. Growing axons of both tracts are transiently very closely apposed to each other. Despite this spatial proximity, axons from
Adler, Alvarado-Mallart, Bixby, Bixby, Bonhoeffer, Bonhoeffer, Boxberg, Bray, Cohen, Edelman, Elsdale, Goldberg, Goldberg, Halfter, Halfter, Halfter, Halfter, Halfter, Halfter, Halfter, Hamburger, Hankin, Harris, Haydon, Kapfhammer, Kapfhammer, Kapfhammer, Katz, Kroger, Kröger, Lagenaur, LaVail, Letourneau, Letourneau, Liesi, Linser, Mattson, McCobb, McLoon, O'Leary, Puelles, Rager, Raper, Rathjen, Rogers, Rosner, Sanes, Silver, Silver, Smalheiser, Thanos, Tomaselli, Vanselow, Walter, Wictorin, Zipser   +55 more
core   +1 more source