Results 81 to 90 of about 2,517,057 (344)

Difficulties in differentiating thin basement membrane disease from Alport syndrome

, 2016
We examined a group of 83 patients (57 children and 26 adults) with thin basement membrane disease and 17 patients with Alport syndrome. We compared the clinical data and, above all, the morphological patterns of both disease entities, with particular ...
Aldona Woźniak, Wiesława Salwa-Żurawska, Jakub Żurawski, Paweł Burchardt, Marcin Grochowalski, Monika Seget, Jerzy Moczko   +6 more
core   +1 more source

Tri-Layered Full-Thickness Artificial Skin Incorporating Adipose-Derived Stromal Vascular Fraction Cells, Keratinocytes, and a Basement Membrane

Bioengineering
Tissue-engineered artificial skin has the potential to enhance wound healing without necessitating extensive surgical procedures or causing donor-site morbidity.
Jung Huh, Seong-Ho Jeong, Eun-Sang Dhong, Seung-Kyu Han, Kyung-Chul Moon   +4 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Basement membrane: Carbohydrates and X-ray diffraction [PDF]

, 1969
Epithelial basement membrane, synthesized by a parietal yolk sac carcinoma in vitro or in the ascites, is free of connective tissue cells and products.
Goldstein, Irwin J., Lee, P. A., I. J. Goldstein, Blasey, K., K. Blasey, P. A. Lee, G. B. Pierces, Pierce, G. B.   +7 more
core   +1 more source

Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture

Cancer Cell International, 2009
Background MCF-10A cells are near diploid and normal human mammary epithelial cells. In three-dimensional reconstituted basement membrane culture, they undergo a well-defined program of proliferation, differentiation, and growth arrest, forming acinar ...
Imbalzano Anthony N, Tatarkova Iva, Imbalzano Karen M, Nickerson Jeffrey A   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Agrin binds to the nerve-muscle basal lamina via laminin. [PDF]

, 1997
Agrin is a heparan sulfate proteoglycan that is required for the formation and maintenance of neuromuscular junctions. During development, agrin is secreted from motor neurons to trigger the local aggregation of acetylcholine receptors (AChRs) and other ...
Brandenberger, R, Ralph Brandenberger, Matthias Gesemann, Gesemann, M., Denzer, A. J., Chiquet, M, Ruegg, M. A., Denzer, A J, Brandenberger, R., Markus A. Ruegg, Matthias Chiquet, Gesemann, M, Ruegg, M A, Chiquet, M., Alain J. Denzer   +14 more
core   +1 more source

Correlated alterations in prostate basal cell layer and basement membrane

International Journal of Biological Sciences, 2009
Our recent studies revealed that focal basal cell layer disruption (FBCLD) induced auto-immunoreactions represented a contributing factor for human prostate tumor progression and invasion. As the basement membrane surrounds and attaches to the basal cell
Aijun Liu, Lixin Wei, William A. Gardner, Chu-Xia Deng, Yan-Gao Man
doaj  

A muscle-epidermis-glia signaling axis sustains synaptic specificity during allometric growth in Caenorhabditis elegans

eLife, 2020
Synaptic positions underlie precise circuit connectivity. Synaptic positions can be established during embryogenesis and sustained during growth. The mechanisms that sustain synaptic specificity during allometric growth are largely unknown.
Jiale Fan, Tingting Ji, Kai Wang, Jichang Huang, Mengqing Wang, Laura Manning, Xiaohua Dong, Yanjun Shi, Xumin Zhang, Zhiyong Shao, Daniel A Colón-Ramos   +10 more
doaj   +1 more source

IgG subclass deposition in diabetic nephropathy

European Journal of Medical Research, 2022
Purpose This study aimed to analyze the distribution of IgG subclass in diabetic nephropathy (DN) and its association with clinicopathological features.
Xuanli Tang, Feng Wan, Qin Zhu, Tian Ye, Xue Jiang, Haichun Yang   +5 more
doaj   +1 more source