Results 51 to 60 of about 36,211 (244)

Glomerulonephritis associated with systemic sclerosis: a case report

Journal of Medical Case Reports, 2023
Background Systemic sclerosis is a multiorgan autoimmune disease that can overlap with other rheumatologic disorders; however, co-occurrence with antineutrophil cytoplasmic antibody-associated vasculitis is rare.
Sepehr Nayebirad, Alireza Ramandi, Fatemeh Nili, Reza Atef-Yekta, Zahra Tamartash, Samira Salehi, Hoda Kavosi   +6 more
doaj   +1 more source

Thin glomerular basement membrane disease [PDF]

Kidney International, 2001
Isolated microscopic hematuria that begins in childhood and is of glomerular origin has a rather limited differential diagnosis, with Alport syndrome, IgA nephropathy, and benign familial hematuria as the most prevalent conditions. In a series of 322 children with persistent hematuria for longer than 6 months, biopsies were classified as IgA ...
openaire   +2 more sources

The Glomerular Basement Membrane [PDF]

, 1981
The basement membrane of the glomerular capillaries of the mammalian kidney has been a favorite object for studies on the structure, function, and composition of basement membranes because of its important biological role in glomerular filtration of macromolecules, and because of the relative ease with which it can be isolated for study, free from ...
openaire   +2 more sources

Membranous nephropathy followed by anti-glomerular basement disease: A case report and review of clinical presentation and treatment

SAGE Open Medical Case Reports, 2018
Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary through autoimmune disease, medication, infection, or malignancy.
Claudius Speer, Matthias Martin Gaida, Rüdiger Waldherr, Christian Nusshag, Florian Kälble, Martin Zeier   +5 more
doaj   +1 more source

Glomerular Basement Membrane Protein Expression and the Diagnosis and Prognosis of Autosomal Dominant Alport Syndrome

Kidney Medicine, 2019
Alport syndrome is a hereditary glomerular nephritis associated with hearing loss and eye abnormalities and is classified as X-linked Alport syndrome, autosomal recessive Alport syndrome, and autosomal dominant Alport syndrome.
Taro Akihisa, Masayo Sato, Yoshie Wakayama, Sekiko Taneda, Shigeru Horita, Orie Hirose, Shiho Makabe, Hiroshi Kataoka, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Kosaku Nitta, Toshio Mochizuki   +12 more
doaj   +1 more source

ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice

Disease Models & Mechanisms, 2016
Collagen IV is a major component of basement membranes, and mutations in COL4A1, which encodes collagen IV alpha chain 1, cause a multisystemic disease encompassing cerebrovascular, eye and kidney defects.
Frances E. Jones, Matthew A. Bailey, Lydia S. Murray, Yinhui Lu, Sarah McNeilly, Ursula Schlötzer-Schrehardt, Rachel Lennon, Yoshikazu Sado, David G. Brownstein, John J. Mullins, Karl E. Kadler, Tom Van Agtmael   +11 more
doaj   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

What is new in the management of rapidly progressive glomerulonephritis?

, 2015
Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB, G. H. B. Greenhall, Salama, AD, A. D. Salama   +3 more
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Nonenzymatic Glycosylation of Glomerular Basement Membrane

Kidney and Blood Pressure Research, 1981
To test the hypothesis that increased nonenzymatic glycosylation contributes to the microangiopathic sequelae of diabetes, we examined the interaction of glucose with basement membranes in vivo and in vitro. The level of nonenzymatic glycosylation, determined by hydroxymethylfurfuraldehyde (HMF) generation, in glomerular basement membrane (GMB ...
M P, Cohen, E, Urdanivia, V Y, Wu
openaire   +2 more sources