Results 11 to 20 of about 32,626 (197)
Alport syndrome results from a myriad of variants in the COL4A3, COL4A4, or COL4A5 genes that encode type IV (basement membrane) collagens. Unlike type IV collagen α1(IV)2α2(IV)1 heterotrimers, which are ubiquitous in basement membranes, α3/α4/α5 have a ...
Dominic Cosgrove, Jacob Madison
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Glomerular basement membrane and related glomerular disease [PDF]
The glomerular basement membrane (GBM) is lined by fenestrated endothelium from the capillary-lumen side and by interdigitating foot processes of the podocytes from the urinary- space side. These three layers of the glomerular capillary wall constitute the functional unit of the glomerular filtration barrier.
Ying Maggie, Chen, Jeffrey H, Miner
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Tubular basement membrane deposits after allogeneic hematopoietic stem cell transplantation
Background Extraglomerular immune complex deposition is rare and only a few membranous nephropathy cases with tubular basement membrane deposits have been reported following allogeneic hematopoietic stem cell transplantation.
Wenyan Zhou +4 more
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Etanercept-Induced Anti-Glomerular Basement Membrane Disease
Anti-glomerular basement membrane (anti-GBM) disease is a rare form of small-vessel vasculitis that typically causes rapidly progressive glomerulonephritis with or without alveolar haemorrhage.
Saif Al-Chalabi +3 more
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Case Report of a Patient with Goodpasture’s Syndrome Who Relapsed While on Hemodialysis
Goodpasture’s syndrome is a rare autoimmune disease in which anti-glomerular basement membrane antibodies damage the glomerular and alveolar basement membrane. Its relapse is very rare, compared to other pulmonary-renal syndromes.
Tuba Elif ŞENEL +7 more
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Introduction Anti-glomerular basement membrane disease is a rare autoimmune disorder characterized by pulmonary hemorrhage, crescentic glomerulonephritis and the presence of circulating anti-glomerular basement membrane antibodies.
Nivera Noel +2 more
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Antiglomerular Basement Membrane Disease [PDF]
AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
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Background We report a previously unrecognized and unreported case of a patient with anti-glomerular basement membrane glomerulonephritis following nintedanib, an orally active small molecule tyrosine kinase inhibitor.
Ibrahim Ismail +3 more
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Mechanisms of Podocyte Detachment, Podocyturia, and Risk of Progression of Glomerulopathies
Background: Glomerulopathies are the main cause of ESRD. Primary or secondary causes of glomerular diseases comprise more than 70% of cases that end up in renal replacement therapies.
Hernán Trimarchi
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The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source

