Results 71 to 80 of about 7,695,341 (360)

Declaração conjunta da XII Reunião ministerial do BASIC sobre mudança do clima : Brasília, Brasil, 20 e 21 de setembro, 2012 [PDF]

open access: yes, 2014
Los representantes de los países miembros del Grupo BASIC se reúnen para tratar el tema del cambio climático y el desarrollo sustentable, entre otras cuestiones.Instituto de Relaciones Internacionales ...
Grupo BASIC
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Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Public Spending in Basic Education in Colombia: Its Contribution to Economic and Social Development

open access: yesRevista IUSTA
Education is a fundamental tool for social transformation, strengthening democracy, and reducing socioeconomic gaps in Colombia. Despite advances in educational coverage, problems related to quality and relevance persist in the educational system, with ...
José Alexander Manjarrés Márquez   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

An egalitarian case for basic income

open access: yes, 1992
In section 1, I set out a general perspective on the nature of egalitarianism and relate it to some familiar conceptions of economic equality. In section 2, I argue in keeping with the popular notion of equality that it makes sense to think of equal ...
Baker, John
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Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Emergent changes and trends in land tenure and land use in Kabale and Kisoro Districts

open access: yes, 1992
The table of contents for this item can be shared with the requester. The requester may then choose one chapter, up to 10% of the item, as per the Fair Dealing provision of the Canadian Copyright ...
Centre for Basic Research, Robert, M.
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Matkalla vastuullisuuteen: Case Basic-Fashion Oy [PDF]

open access: yes, 2021
Tämän opinnäytetyön tavoitteena oli hankkia tutkimustietoa tekstiiliteollisuuden vastuullisuudesta, jotta sitä voitaisiin hyödyntää Basic-Fashionin vastuullisuussuunnitelmassa.
Savaspuro, Satu
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