Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Implication of Sulfatide in Type 1 Diabetes and Multiple Sclerosis. Comment on Root-Bernstein, R. Type 1 Diabetes-Associated Autoantibodies, Sera and T-Cell Receptor Sequences Recognize Myelin Basic Protein: A Novel Peripheral Diabetic Neuropathy-Multiple Sclerosis Connection. <i>Cells</i> 2026, <i>15</i>, 1384. [PDF]
CellsThea R, Buschard K.
europepmc +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Reply: IL-1 Blockade to Resolve Persistent Inflammation After STEMI. [PDF]
JACC Basic Transl SciSager HB.
europepmc +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Integrating Basic Sciences into Dental Education: A Comparative Narrative Review of Curricular Approaches Across Different Countries. [PDF]
Dent J (Basel)Ek G +4 more
europepmc +1 more source
Methods of Basic Draping, v. 2. Basic Bodice II: Back
“Methods of Basic Draping” was produced by FIT in 1982 and is still used today. It’s an FIT classic!Technical supervision, Hedda Gold; fashion illustration, Linda Tain; television supervision, Lee White; produced and directed by Jeffrey Buchman ...
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Relationship Between the Revised Version of the Ability for Basic Movement Scale and Motor Functional Independence Measure Scores and Gain. [PDF]
Jpn J Compr Rehabil SciTakahashi K +3 more
europepmc +1 more source