Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
EN: Book review. HR: Prikaz knjige.
Ivan Basić
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Role of Fort Asa City as a Basic Defense of The Bima Kingdom in 1667
The resistance of the Bima people in defending the kingdom's territory from Dutch colonial colonialism has taken quite a long time, where Asakota Fort has an important role as a maritime defense strategy.
Subari Subari, Anwar Anwar
doaj +1 more source
Computer- Aided Setup Planning of Machine Tools For Different Machining Operations [PDF]
Most of machining &manufacturing operations done by differentmachining machine tools, where the machining parts pass through differentmachining operations, starting from raw material to the final product.
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A comparative investigation of personality traits and learning modes in basic, engineering and human sciences' students of Islamic Azad University in Mazandaran province [PDF]
he aim of the present research was to conduct a comparative investigation of personality traits and learning modes in basic, engineering and human sciences' students of Islamic Azad University in Mazandaran province.
Arsalan Khanmohammadi (MA) +2 more
doaj
Financing of small-enterprise business and its importance in economic activity encouraging [PDF]
Paper entitled "Financing and importance of small business to encourage economic activity," deals with the problem which is an adequate model of financing activities of small businesses and what their importance in encouraging commercial activities.
Bašić Dragana, Bašić Slavica
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

