Results 31 to 40 of about 5,412,567 (302)

Basic Life Support Knowledge and Its Associated Factors Among a Non-Medical Population in Gondar Town, Ethiopia

open access: yesOpen Access Emergency Medicine, 2020
Chilot Kassa Mekonnen,1 Addis Bilale Muhye2 1Department of Medical Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Department of Pediatric Nursing, School of Nursing, College of Medicine and ...
Mekonnen CK, Muhye AB
doaj  

Financing of small-enterprise business and its importance in economic activity encouraging [PDF]

open access: yesEkonomski Pogledi, 2013
Paper entitled "Financing and importance of small business to encourage economic activity," deals with the problem which is an adequate model of financing activities of small businesses and what their importance in encouraging commercial activities.
Bašić Dragana, Bašić Slavica
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

EFFECT OF TRAINING ON CAREER PERFORMANCE OF NIGERIA SECURITY AND CIVIL DEFENSE CORPS (NSCDC) PERSONNEL IN KADUNA STATE COMMAND

open access: yesInternational Studies Journal, 2022
This paper examines the effect of training on career performance of Nigeria Security and Civil Defense Corps (NSCDC) Personnel in Kaduna state command to examine the impact and types of training required for effective career performance of NSCDC ...
LEKSHUM SUNDAY AMOS
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Basics of Basics

open access: yes
Existential core. Core directives Nature If you don't want to live, there won't be a continuation. Logic of the Great, Logic of the Wise ΧΡ ΩΝ Ил-Всевышний-Отец Богов :Бог-Сознания Вселенной выявляющий своё присутствие через осознанные свет и звуки , источник жизни и истины.
openaire   +5 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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