Results 121 to 130 of about 3,095,661 (250)
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
On the balance between strategic-basic and applied agricultural research [PDF]
Strategic‐basic research refers to basic research conducted in strategically selected areas expected to be of social benefit. Recent literature on the processes of basic research and its links to applied research has not been widely discussed in relation
Pannell, David J.
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The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Methods of Basic Draping, v. 2. Basic Bodice II: Back
“Methods of Basic Draping” was produced by FIT in 1982 and is still used today. It’s an FIT classic!Technical supervision, Hedda Gold; fashion illustration, Linda Tain; television supervision, Lee White; produced and directed by Jeffrey Buchman ...
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, 1960 These biennial reports are summaries of the activities of this agency. They were extracted from a series of Kansas agency reports covering over 100 state agencies and institutions bound together for each biennium., 1959/1960 - 1979/1980.
Kansas. State Board of Basic Science Examiners.
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Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
An audit of some health facilities and equipment for neonatal resuscitation in south-south Nigeria
Nigerian Journal of PaediatricsBackground: Neonatal Mortality rates continue to be high in spite of the general decline in under-5 mortality rates in Nigeria. Available evidence has shown that the availability of a skilled birth attendant and equipment for basic neonatal resuscitation
Oloyede IP , Udo PA
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Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source