Results 111 to 120 of about 7,695,341 (360)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Basic Income Network Scotland: Review of Citizens’ Basic Income Feasibility Study
, 2021 Interest in universal basic income has mushroomed in recent years in response to increasing employment insecurity and in-work poverty, with pilots and trials conducted or planned in several locations, and support from a growing number of politicians. The
Miller, Annie +2 more
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Inequity in access to palliative care services worldwide and in Slovenia
Radiology and OncologyPalliative care aims to enhance the quality of life of patients and their families facing progressive and incurable disease by addressing physical, psychological, social, and spiritual challenges.
Golob Nena, Moltara Maja Ebert
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
DIAGNOSTICS OF LEVELS OF FUTURE PRIMARY SCHOOL TEACHERS’ INFORMATIVE COMPETENCE
Ìнформаційні технології в освіті, 2013 The article describes the main structural components of future primary school teachers’ informative competence according to modern researches, diagnostic methods and results of future primary school teachers’ informative competence levels are ...
V. Kotkova
doaj
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Visual Basic 2012 Programmer's Reference
, 2012 Rod Stephens is a VB programming guru and the author of more than two dozen programming books, including Stephens' Visual Basic Programming 24-Hour Trainer. He also writes frequently for such magazines as Visual Basic Developer, Visual Basic Programmer's
Stephens, Rod
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Growing Trends of Orientation Web Pages
Journal of College Orientation, Transition, and Retention, 2000 David F. Rielley
doaj +1 more source