Results 101 to 110 of about 5,423,570 (303)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Separating the basic logics of the basic recurrences
This paper shows that, even at the most basic level, the parallel, countable branching and uncountable branching recurrences of Computability Logic (see http://www.cis.upenn.edu/~giorgi/cl.html) validate different principles.
openaire +3 more sources
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
PIC BASIC projects : 30 projects using PIC BASIC and PIC BASIC PRO /
A wealth of simple and advanced projects to show how PIC BASIC can be used to program the most widely used microcontroller on the market.Includes index.Print version record.Front Cover; PIC BASIC Projects: 30 Projects Using PIC BASIC and PIC BASIC PRO ...
Ibrahim, Dogan.
core
Basic writing (un)written : a critical discourse analysis and genealogy of developmental English in Texas [PDF]
textThe purpose of this study was to investigate the discourses that author basic writing in Texas and question how instructors of basic writing at a community college are constructed as well as constructive through discursive practices.
Forell, Kristy Leigh Hamm, 1977-
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Trip Report on the Appalachian Adult Basic Education Special Project [PDF]
A rough draft of the trip report on the Appalachian Adult Basic Education Special Project submitted by Appalachian Adult Basic Education Demonstration Center circa ...
Appalachian Adult Basic Education Demonstration Center
core
Of the basic right of access to justice
Do direito fundamental de acesso à justiça
The access to justice is here studied as right basic. The article has for target the conceptualization of this guarantee and the identification of the main problems that presents. It analyzes the protection of the rights and offers proposals aiming at to
Mauro Vasni Paroski
doaj
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source

