Results 51 to 60 of about 5,412,567 (302)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Basic Products Corporation Wholesale Price List

open access: yes, 1918
After U.S. entry into the war, Hoosier businessmen travelled to Washington to see about procuring war contracts for Indiana industries. The state’s industries furnished war materials on a large scale, their total value approximating $300,000,000.
Basic Products Corporation
core  

Emergent changes and trends in land tenure and land use in Kabale and Kisoro Districts

open access: yes, 1992
The table of contents for this item can be shared with the requester. The requester may then choose one chapter, up to 10% of the item, as per the Fair Dealing provision of the Canadian Copyright ...
Centre for Basic Research, Robert, M.
core   +1 more source

Missing the Forest for the Trees

open access: yesCanadian Journal of Bioethics
This response expands on Wyzynski’s focus of the importance of fostering elementary ethics deliberation and education within hospitals. In particular, it highlights that most of the clinical ethicist’s work revolves around basic, fundamental ethical ...
Jordan Potter
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Basic Biologocal Chemistry

open access: yes, 1968
x.;ill.;527 hal.; 25 ...
Basic Biologocal Chemistry
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Land to tillers or tillers to land : the existing forms of land tenure systems in Mpigi District

open access: yes, 1994
The table of contents for this item can be shared with the requester. The requester may then choose one chapter, up to 10% of the item, as per the Fair Dealing provision of the Canadian Copyright ...
Centre for Basic Research, Bikaako, W.
core   +1 more source

Mailo land tenure system, customary land rights and claims in Buganda : a case study of Nakasongola

open access: yes, 1998
The table of contents for this item can be shared with the requester. The requester may then choose one chapter, up to 10% of the item, as per the Fair Dealing provision of the Canadian Copyright ...
Centre for Basic Research   +1 more
core   +1 more source

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