Results 41 to 50 of about 11,821,405 (264)

The basic sequence problem

open access: yes, 1994
We construct a quasi-Banach space $X$ which contains no basic ...
Kalton, Nigel J.
core   +2 more sources

Basic nets in the projective plane [PDF]

open access: yes, 2014
The notion of basic net (called also basic polyhedron) on $S^2$ plays a central role in Conway's approach to enumeration of knots and links in $S^3$. Drobotukhina applied this approach for links in $RP^3$ using basic nets on $RP^2$.
Orevkov, S. Yu.
core   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Cultura organizacional desde la teoría de Edgar Schein: Estudio fenomenológico

open access: yesCLIO América, 2015
The article presents the study of a phenomenon of corporate life from the description of the organizational culture in three organizations of educational character in Santa Marta-Colombia, whose objective was guided to describe the organizational ...
Lilibeth Pedraza-Álvarez   +3 more
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

From Kyoto Protocol to Paris Agreement: An Analysis of Global Climate Regime Changes Based on a Study of the Evolution of Green Gases Emissions Profiles

open access: yesDesenvolvimento e Meio Ambiente, 2017
This paper uses the notion of climate regime provided by the International Relations literature and by interdisciplinary approaches on climate change.
Maria Cristina Oliveira Souza   +1 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Weighted entropy: basic inequalities

open access: yes, 2017
This paper represents an extended version of an earlier note [10]. The concept of weighted entropy takes into account values of different outcomes, i.e., makes entropy context-dependent, through the weight function.
Kelbert, Mark   +2 more
core   +1 more source

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