Results 41 to 50 of about 7,695,341 (360)
International Studies Journal, 2022 This paper examines the effect of training on career performance of Nigeria Security and Civil Defense Corps (NSCDC) Personnel in Kaduna state command to examine the impact and types of training required for effective career performance of NSCDC ...
LEKSHUM SUNDAY AMOS
doaj
Model Inversion Attacks that Exploit Confidence Information and Basic Countermeasures
Conference on Computer and Communications Security, 2015 Machine-learning (ML) algorithms are increasingly utilized in privacy-sensitive applications such as predicting lifestyle choices, making medical diagnoses, and facial recognition.
Matt Fredrikson +2 more
semanticscholar +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research
Nature Reviews Microbiology, 2019 Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern pathogens. The same organism that lives as a commensal and is transmitted in both health-care and community settings is also a leading cause of bacteraemia ...
N. Turner +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A guide to vaccinology: from basic principles to new developments
Nature reviews. Immunology, 2020 Immunization is a cornerstone of public health policy and is demonstrably highly cost-effective when used to protect child health. Although it could be argued that immunology has not thus far contributed much to vaccine development, in that most of the ...
A. Pollard, E. Bijker
semanticscholar +1 more source
The mouse prostate: a basic anatomical and histological guideline
, 2016 Despite substantial similarities in embryological, cellular and molecular biology features, human and mouse prostates differ in organ morphology and tissue architecture.
Oliveira, Daniel S.M. +5 more
core +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source