Results 91 to 100 of about 3,773,115 (336)
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Scientific Reports, 2021 Stroke and cognitive impairment are common in older population. They often occur together and their combined effects significantly increase disability in both basic (BADLs) and instrumental (IADLs) activities of daily living.
Pi-Hsia Lee +5 more
semanticscholar +1 more source
ElderSim: A Synthetic Data Generation Platform for Human Action Recognition in Eldercare Applications [PDF]
arXiv, 2020 To train deep learning models for vision-based action recognition of elders' daily activities, we need large-scale activity datasets acquired under various daily living environments and conditions. However, most public datasets used in human action recognition either differ from or have limited coverage of elders' activities in many aspects, making it ...
arxiv
Satisfaction and Performance of Software Developers during Enforced Work from Home in the COVID-19 Pandemic [PDF]
Empirical Software Engineering, 2023, 2021 Following the onset of the COVID-19 pandemic and subsequent lockdowns, the daily lives of software engineers were heavily disrupted as they were abruptly forced to work remotely from home. To better understand and contrast typical working days in this new reality with work in pre-pandemic times, we conducted one exploratory (N = 192) and one ...
arxiv
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
The newly revised interview for deteriorations in daily living activities in dementia (R-IDDD2): distinguishing initiative from performance at assessment [PDF]
, 2016 Background: Minimal evidence exists on the detailed deficits in complex instrumental activities of daily living (IADLs) in mild dementia. The aim of this study was twofold, to validate a revised questionnaire focusing measuring the initiative and ...
Ballard +11 more
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
BMC GeriatricsIntroduction Functional disability in older adults refers to difficulties in performing daily activities. It is usually evaluated based on an individual’s ability to carry out basic activities of daily living and instrumental activities of daily living ...
Baye Tsegaye Amlak +5 more
doaj +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Neurocognitive impairment is associated with lower health literacy among persons living with HIV infection. [PDF]
, 2014 This study sought to determine the effects of HIV-associated neurocognitive disorders (HAND) on health literacy, which encompasses the ability to access, understand, appraise, and apply health-related information.
Blackstone, Kaitlin +6 more
core +1 more source