Results 101 to 110 of about 1,153,423 (284)

Effectiveness of Day Care Services of Karaj Kahrizac Rehabilitation Center on Activities of Daily Living Among Older People, 2010 April-2011 March

open access: yesSālmand, 2013
Objectives: Day care centers try to give day care services to old people to improve their functional abilities and inhibit their unnecessary admition in residential care centers.
Mohsen Rahimi   +6 more
doaj  

Daily Stress Recognition from Mobile Phone Data, Weather Conditions and Individual Traits

open access: yes, 2014
Research has proven that stress reduces quality of life and causes many diseases. For this reason, several researchers devised stress detection systems based on physiological parameters.
Cohen S.   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Disability relating to basic and instrumental activities of daily living among elderly subjects.

open access: yesRevista de saude publica, 2009
OBJECTIVE: To assess the prevalence of disability and associated factors in elderly, by focusing on basic and instrumental activities of daily living. METHODS: This was a cross-sectional study on 598 subjects aged 60 years or over who were selected through two-stage cluster sampling in Pelotas, Southern Brazil, between 2007 and 2008.
Del Duca, Giovâni Firpo   +2 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Basic and instrumental activities in relation to the situation of fragility

open access: yesINFAD, 2019
This descriptive transversal research studies frailty situation in older adults and basic and instrumental activities of daily living relationship through a 194 old institucionalized people sample.
Miriam Santamaría -Peláez   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Determination of the perceptions of sports managers about sport concept: A metaphor analysis study [PDF]

open access: yes, 2018
The aim of this research is to determine the perceptions of sport managers in Turkey on the concept of sport by means of metaphors. 74 sport managers participated in the research.
Kurtipek, S., Sönmezoğlu, Uğur
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Ageing, income and living standards: evidence from the British Household Panel Survey [PDF]

open access: yes, 2009
In Britain, older people have lower average incomes and a higher risk of income poverty than the general population. Older pensioners are more likely to be in poverty than younger ones.
Banks   +14 more
core   +1 more source

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