Results 51 to 60 of about 1,150,117 (291)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The bidirectional relationship between activities of daily living and frailty during short-and long-term follow-up period among the middle-aged and older population: findings from the Chinese nationwide cohort study

open access: yesFrontiers in Public Health
ObjectiveFrailty and activities of daily living (ADL) disability are common conditions among older population. Studies on the bidirectional relationship between frailty and ADL are limited.
Xiaoping Li   +12 more
doaj   +1 more source

A Profile of Frail Older Americans and Their Caregivers [PDF]

open access: yes, 2006
Provides a profile of older Americans and their caregivers, focusing on people age 65 and older who are not in nursing homes, and those with severe disabilities.
Joshua M. Wiener, Richard W. Johnson
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Effect of an educational intervention on nurses’ competence in activities of daily living support in end-of-life care using a pretest–posttest repeated measures design

open access: yesBMC Palliative Care, 2023
Background Most patients in specialized palliative care units need nursing support to perform activities of daily living (ADL), such as using a toilet or transferring out of a bed or chair.
Heidrun Gattinger   +5 more
doaj   +1 more source

Effects of multisensory stimulation on a sample of institutionalized elderly people with dementia diagnosis: a controlled longitudinal trial [PDF]

open access: yes, 2014
[Abstract] Long-term effects of multisensory stimulation were assessed using a ‘‘Snoezelen’’ room on older residents with dementia. Thirty patients were randomly assigned to 3 groups: multisensory stimulation environment (MSSE) group, individualized ...
Buján, Ana   +5 more
core   +2 more sources

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Functional disability in basic and instrumental activities of daily living among older adults globally: a systematic review and meta-analysis

open access: yesBMC Geriatrics
Introduction Functional disability in older adults refers to difficulties in performing daily activities. It is usually evaluated based on an individual’s ability to carry out basic activities of daily living and instrumental activities of daily living ...
Baye Tsegaye Amlak   +5 more
doaj   +1 more source

Perception of family support among low-income elderly and associated factors [PDF]

open access: yes, 2014
This study aims to identify the perception of family support among low-income elderly and associated factors. It is cross- sectional study with a sample of 235 elderly residents of Jequié, Bahia, Brazil.
Costa, Isabelle Katherinne Fernandes   +5 more
core  

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