Results 171 to 180 of about 5,804,591 (298)

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Interface Engineering of CoS₂/Co(OH)F Heterostructures for In Situ Co⁴⁺ Formation and Enhanced Oxygen Evolution Reaction. [PDF]

ChemSusChem
Meng Y, Zhong B, Zeng D, Zeng C, Du B, Zhang W, Zhang P, Feng L, Wang Y, Shanmugam S, Gao Q.   +10 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Penumbra-derived small extracellular vesicles carry pathogenic RNA driving remote damage after cortical infarction. [PDF]

Brain
Deng D, Wu Y, Wu P, Tan N, Li X, Su X, Chen W, Zhang X, Mai H, Xu A, Lu D.   +10 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

A Rigid-Flexible Polyinterface Enabling Molecular-Level Dual-Ion Regulation for Ultrastable Lithium Metal Batteries. [PDF]

Adv Mater
He G, Guo J, Yang L, Ou G, Liu W, Wang X.   +5 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Acid-base bifunctional porous liquids. [PDF]

Nat Commun
Qiu L, Wang T, Liu H, Ganesan A, Li E, Siniard KM, Hu JZ, He L, Nagy G, Ivanov AS, Wang X, Gallington LC, Cooley V, Jiang DE, Mahurin SM, Wang Y, Yang Z, Dai S.   +17 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Tunable dislocations overcome mechano-functional tradeoff in perovskite oxides. [PDF]

Sci Adv
Zhang J, Lu W, Fang X.
europepmc   +1 more source