Results 41 to 50 of about 16,976,151 (295)

Utilization of Basic Health Services at Primary Health Care Facilities During COVID-19 Pandemic

open access: yesJournal of Nepal Health Research Council, 2023
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Anita Basnet   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Other title: Report from the Health Care Access Improvement Panel

open access: yes, 2015
application/pdf"2004 Senate Substitute for HB 2912 and House Substitute for SB 12 established the Health Care Access Improvement Program, which uses an annual assessment on inpatient services provided by hospitals to improve and expand health care ...
Health Care Access Improvement Panel (Kan.).
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

واقع تأثير السلوكيات الذاتية و الجماعية على طلب خدمات الهياكل الصحية القاعدية في الجزائر : دراسة حالة عيادات متعددة الخدمات في المنطقة الصحية الشرقية

open access: yesRevue Economie, Gestion et Société, 2017
This paper is the first inventory of individual and collective behavioral influences on the demand for local care in Algeria. Long analyzed under the economic aspect, inequalities in health are today apprehended according to a multitude of sociological ...
نصر الدين عيساوي
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Abstracts From the 2024 Health Care Systems Research Network (HCSRN) Annual Conference, Milwaukee, Wisconsin [PDF]

open access: yes
The Health Care Systems Research Network (HCSRN) comprises 20 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate ...
Research Network, Health Care Systems
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Other title: Policies and Procedures : for Administration of the Health Care Provider Insurance Availability Act; Other title: Administration of the Health Care Provider Insurance Availability Act

open access: yes, 2017
[Revised].; "Adopted March 6, 2008. Amended July 10, 2008; July 9, 2009; May 13, 2010; Nov. 18, 2010; July 10, 2014; Sep. 10, 2015; May 11, 2017; September 14, 2017.""The Kansas Health Care Stabilization Fund was created in 1976 by enactment of the ...
Kansas. Board of Governors of the Health Care Stabilization Fund.
core   +1 more source

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