Results 61 to 70 of about 16,976,151 (295)

Abstracts From the 2025 Health Care Systems Research Network (HCSRN) Annual Conference, St. Louis, Missouri

open access: yes
The Health Care Systems Research Network (HCSRN) comprises 19 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate ...
Research Network, Health Care Systems
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Continuing health care education: concepts and practices of nurses in basic health units

open access: yesRevista Eletrônica de Enfermagem, 2014
Continuing education in health care is a strategy for constructing new health care and nursing practices. This study aimed to identify the concepts and practices of continuing education in health held by primary care nurses in the municipalities of the ...
Priscila Orlandi Barth   +3 more
doaj   +1 more source

Basics of health care in physiotherapy

open access: yes, 2022
Kada je riječ o zdravstvenoj njezi, danas realiziramo aktivnosti koje omogućavaju medicinskim sestrama provoditi zdravstvenu njegu prema najboljim standardima sestrinske prakse i to zahvaljujući Hrvatskoj komori medicinskih sestara i pisanim izdanjima kojima sam se vodila u izradi ovoga priručnika. U tekstovima će biti prikazan proces zdravstvene njege
openaire   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Pre-activated lyophilized platelets show non-inferior hemostatic effect compared with fresh platelets in rabbits with traumatic bleeding and shock

open access: yesPlatelets
Background A high activation level is a normal characteristic of lyophilized platelets (LPs); however, the effects of this activation level on the efficacy and safety of LPs after transfusion are debated.Objectives We aimed to test the efficacy and ...
Chenglin Dai   +7 more
doaj   +1 more source

Knowledge of Family Health Strategy professionals regarding the Academia da Cidade Program (ACP) in the city of Recife

open access: yesRevista Brasileira de Atividade Física e Saúde, 2016
The aim of this study was to assess the knowledge of Family Health Strategy (FHS) professionals regarding the Academia da Cidade Program (ACP) in Recife.
Vanessa Moura   +5 more
doaj   +1 more source

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