Results 71 to 80 of about 16,976,151 (295)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

The Connecticut Office of Health Care Access 2004 Small Employer Health Insurance Survey-focus on results /

open access: yes, 2004
Title from caption.; "Planning tomorrow's health care system today."; "November 2004."; Updates: Employer-sponsored health insurance / Office of Health Care Access. Hartford, CT : Office of Health Care Access, [2001]

core   +1 more source

Prevalence of musculoskeletal pain in climacteric women of a Basic Health Unit in São Paulo/SP

open access: yesRevista Dor, 2017
BACKGROUND AND OBJECTIVES: The objective of this study was to evaluate the prevalence of musculoskeletal pain in climacteric women of a Basic Health Unit in Sao Paulo.
Anny Caroline Dedicação   +5 more
doaj   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Other title: Availability and utilization of health care services at acute care hospitals and federally qualified health centers fiscal year 2010

open access: yes, 2011
"As required by Connecticut General Statutes (C.G.S.) section 19a-634 this report is one of three components of the Department of Public (DPH) Health Office of Health Care Access' (OHCA) approach to planning for Connecticut's health care system"--P. 4.; "

core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Health care systems in transition: United Kingdom

open access: yes, 1999
vii, 117 p.The Health Care Systems in Transition (HiT) profiles are country-based reports that provide an analytical description of each health care system and of reform initiatives in progress or under development.
European Observatory on Health Systems and Policies   +1 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Long-term care in developing countries : ten case studies / editors: J. Brodsky, J. Habib and M. Hirschfeld [PDF]

open access: yes, 2003
Prepared in collaboration with the World Health Organization and the JDC-Brookdale Institute, the WHO Collaborating Centre for Health and Long-Term Care Policy and Research461 ...
World Health Organization   +4 more
core  

Home - About - Disclaimer - Privacy