Results 161 to 170 of about 15,589,079 (272)

Frontal brain activity assessment during basic life support skill acquisition and transfer in serious game based learning environments. [PDF]

PLoS One
Aksoy ME, Polat MD, Shewokis PA, Kitapcioglu D, Usseli T, Agrali A, Yöner SI, Izzetoglu K.   +7 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Comparing Outcomes of Out-of-hospital Cardiac Arrest Between Prehospital Basic Life Support and Advanced Life Support

International Journal of Gerontology, 2011
Ding-Kuo Chien
doaj   +1 more source

Evaluation of Knowledge and Anxiety Levels in Caregivers of Children With Heart Disease Before and After Basic Life Support Training: A Preliminary Study. [PDF]

Cureus
Dabrowska A, Palczynski P, Meyer-Szary J, Jakitowicz K, Siemiński M, Kusmierz Z, Kwiatkowska J.   +6 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Comparing video-based and four-step simulation training in paediatric basic life support: a pilot randomised controlled study. [PDF]

BMJ Paediatr Open
Thabet F, Besbes H, Ajmi H, Zayani S, Chemli J, Chouchane S.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Relationship Between Body Mass Index and Chest Compression Quality Following Standardized Basic Life Support Training in Nurses: A Prospective Simulation Study. [PDF]

Healthcare (Basel)
Kuvvet Yoldaş T, Gürsoy Çirkinoğlu G, Salman Önemli C.   +2 more
europepmc   +1 more source

Basic Life Support

THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA, 2018
Hiroya WAKAMATSU, Kensuke YAMADA, Satoshi KATSUTA, Kiyotaka SHIRAMOTO, Satoshi MATSUMOTO, Mishiya MATSUMOTO   +5 more
openaire   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source