Results 31 to 40 of about 251,918 (226)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
An Eulerian projection method for quasi-static elastoplasticity [PDF]
, 2015 A well-established numerical approach to solve the Navier--Stokes equations for incompressible fluids is Chorin's projection method, whereby the fluid velocity is explicitly updated, and then an elliptic problem for the pressure is solved, which is used ...
Bouchbinder, Eran +2 more
core +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Research on Aerodynamic Optimization Design of High Lift Airfoil Based on Deep Learning and MOEA/D
Taiyuan Ligong Daxue xuebaoPurposes Aiming at the performance conflict between optimization parameters in prior optimization method, a hybrid optimization model based on MOEA/D is proposed, which integrates CNN and genetic algorithm into MOEA/D framework to balance the correlation
SHEN Yongqiang +3 more
doaj +1 more source
The Fundamental Concepts of Classical Equilibrium Statistical Mechanics
, 2003 A critical examination of some basic conceptual issues in classical statistical mechanics is attempted, with a view to understanding the origins, structure and statuts of that discipline.
Volchan, Sergio B.
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Oil & Gas Science and Technology, 2006 Computational Fluid Dynamics (CFD) and its applications have developed quite rapidly during the last ten years. This fast growing hybrid branch of Mechanics and Mathematics is certainly to be considered as a potentially useful and efficient tool in the ...
Trambouze P.
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
On buoyant convection in binary solidification [PDF]
, 2005 We consider the problem of nonlinear steady buoyant convection in horizontal mushy layers during the solidification of binary alloys. We investigate both cases of zero vertical volume flux and constant pressure, referred to as impermeable and permeable ...
Okhuysen, Brett S., Riahi, Daniel N.
core
Simulation of flows with violent free surface motion and moving objects using unstructured grids [PDF]
, 2007 This is the peer reviewed version of the following article: [Löhner, R. , Yang, C. and Oñate, E. (2007), Simulation of flows with violent free surface motion and moving objects using unstructured grids. Int. J. Numer. Meth. Fluids, 53: 1315-1338.
Löhner, Rainald +2 more
core +4 more sources