Results 41 to 50 of about 115,261,517 (234)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Numerical Simulations of turbulent thermal convection in a domain composed of a pure-fluid region and an immersed heated porous medium

open access: yes, 2022
Heat transfer and fluid flow in domains that include a pure- fluid region and porous region are encountered in many natural phenomena as well as in technological applications.
14th European Fluid Mechanics Conference   +2 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Influence of the grain size and the fluid viscosity on the collapse of submerged sand columns

open access: yes, 2022
Granular flows are ubiquitous in natural phenomena and are also used in various industrial applications. Nonetheless, they exhibit counter-intuitive behaviour as well as complex rheological behaviour, making them challenging to fully understand and model.
14th European Fluid Mechanics Conference   +2 more
core  

Molecular Dynamics Simulation in Arbitrary Geometries for Nanoscale Fluid Mechanics [PDF]

open access: yes, 2008
Simulations of nanoscale systems where fluid mechanics plays an important role are required to help design and understand nano-devices and biological systems.
Macpherson, Graham Bruce
core   +6 more sources

NEW APPROACHES IN CHEMICAL ENGINEERING AND EDUCATION

open access: yesJournal of the Turkish Chemical Society Section B: Chemical Engineering
This study explores the definition, brief history, development trajectory, societal duties, and contributions to technological developments of chemical science and chemical engineering.
Kuddis Büyükakıllı
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Novel Idea and Disruptive Technologies for the Exploration and Research of Deep Earth

open access: yes工程科学与技术, 2017
:President Xi Jinping has recently declared that marching toward the deep earth is a strategically scientific and technological challenge we must overcome.In China,the exploitation of deep earth resources has become an important direction for the future ...
谢和平   +5 more
doaj  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Fluid Mechanics

open access: yes
Fluid mechanics has been a topic of great practical and research interest for many centuries. However, this field of research is still young and vigorous, thanks to tremendous opportunities that have been provided by modern computational and experimental
Kravalis, Kalvis   +3 more
core   +2 more sources

Home - About - Disclaimer - Privacy