Association Between Genetic Ancestry and Multiple Sclerosis Severity
Objective The objective of this study was to determine whether genetic ancestry is associated with differences in the clinical course of multiple sclerosis (MS). Methods Participants with MS living in the United Kingdom >18 years old were recruited from 2021 to 2025 and genotyped from saliva using a commercial array. Genetic ancestry was inferred using
Benjamin M. Jacobs +32 more
wiley +1 more source
Beyond Autonomy, Competence, and Relatedness: A Comprehensive Scale for Basic Psychological Needs and Novelty in Exercise. [PDF]
Bártolo V +9 more
europepmc +1 more source
Memory and Plasma pTau217 Refine Prognosis in Down Syndrome
Individuals with Down syndrome (DS) are at high risk for Alzheimer's disease (AD), yet accessible tools for routine clinical screening of AD in individuals with DS remain limited. Using data from the Alzheimer Biomarker Consortium‐Down Syndrome (ABC‐DS), we show that integrating plasma pTau217 with performance on the modified cued recall task ...
Casey R. Vanderlip +62 more
wiley +1 more source
Between "we" and "well-being": Do basic psychological needs mediate the relationship between interdependent self-construal and adolescent subjective well-being? [PDF]
Lazić M +7 more
europepmc +1 more source
Purpose To systematically review and analyze the existing literature on the use of the Forgotten Joint Score‐12 (FJS‐12) in patients undergoing anterior cruciate ligament reconstruction (ACLR), with the aim of evaluating its effectiveness as a complementary tool to traditional patient‐reported outcome measures (PROMs) in assessing postoperative ...
Helena Son +6 more
wiley +1 more source
The relationship between the social media advertising content characteristics and the advertising effectiveness of female users: a moderated mediation model based on basic psychological needs. [PDF]
Han Y.
europepmc +1 more source
Purpose To develop an artificial intelligence‐based algorithm to predict success of nonoperative treatment in degenerative posterosuperior tears and to identify the most influential features. Methods Patients with degenerative rotator cuff tears initially treated nonoperatively were enrolled prospectively from January 2022 to November 2024.
Santiago Gabardo +8 more
wiley +1 more source
Basic psychological needs and psychache: associations with cognitive reappraisal and stress mindset in a cross-sectional sample. [PDF]
Hou Y, Li H, Ma W, Wu J, Wang Y, Liu J.
europepmc +1 more source
Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker +17 more
wiley +1 more source

