Results 91 to 100 of about 1,179,686 (304)
A mathematical model for the novel coronavirus epidemic in Wuhan, China
Mathematical Biosciences and Engineering, 2020 We propose a mathematical model to investigate the current outbreak of the coronavirus disease 2019 (COVID-19) in Wuhan, China. Our model describes the multiple transmission pathways in the infection dynamics, and emphasizes the role of the environmental
Chayu Yang, Jin Wang
doaj +1 more source
Stochastic epidemic models: a survey [PDF]
, 2009 This paper is a survey paper on stochastic epidemic models. A simple stochastic epidemic model is defined and exact and asymptotic model properties (relying on a large community) are presented.
Britton, Tom
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Mathematical model for the control of measles
Journal of Applied Sciences and Environmental Management, 2018 We proposed a mathematical model of measles disease dynamics with vaccination by considering the total number of recovered individuals either from natural recovery or recovery due to vaccination.
O.J. Peter +4 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Mathematical Biosciences and Engineering, 2007 Heterogeneity in sexual behavior is known to play an important role in the spread of HIV. In 1986, a mathematical model based on ordinary differential equations was introduced to take into account the distribution of sexual activity.
Nicolas Bacaër +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Epidemic threshold conditions for seasonally forced SEIR models
Mathematical Biosciences and Engineering, 2005 In this paper we derive threshold conditions for eradication of diseases that can be described by seasonally forced susceptible-exposed-infectious-recovered (SEIR) models or their variants. For autonomous models, the basic reproduction number $\mathcal{R}
Junling Ma, Zhien Ma
doaj +1 more source
The basic reproduction number of vector-borne plant virus epidemics
Virus Research, 2017 The basic reproduction number R0 is a key parameter in plant disease epidemiology, which largely determines whether or not an epidemic will occur in a plant population. The next generation matrix approach to deriving and calculating the basic reproduction number of a plant virus epidemic is described.
Van den Bosch, F, Jeger, MJ
openaire +4 more sources