Results 91 to 100 of about 504,094 (304)

A mathematical model for Vibrio-phage interactions

open access: yesMathematical Biosciences and Engineering, 2021
A cholera model has been formulated to incorporate the interaction of bacteria and phage. It is shown that there may exist three equilibria: one disease free and two endemic equilibria.
Christopher Botelho   +4 more
doaj   +1 more source

On the Basic Reproduction Number of Reaction-Diffusion Epidemic Models

open access: yesSIAM Journal on Applied Mathematics, 2019
The basic reproduction number $R_0$ serves as a threshold parameter of many epidemic models for disease extinction or spread.
Pierre Magal, G. Webb, Yixiang Wu
semanticscholar   +1 more source

Spatial dynamics and the basic reproduction number of the 1991–1997 Cholera epidemic in Peru

open access: yesPLoS Neglected Tropical Diseases, 2020
After being cholera free for over 100 years, Peru experienced an unprecedented epidemic of Vibrio cholerae O1 that began in 1991 and generated multiple waves of disease over several years.
A. Smirnova   +6 more
semanticscholar   +1 more source

The basic reproduction number in epidemic models with periodic demographics

open access: yesJournal of Biological Dynamics, 2009
Patterns of contact in social behaviour and seasonality due to environmental influences often affect the spread and persistence of diseases. Models of epidemics with seasonality and patterns in the contact rate include time-periodic coefficients, making the systems nonautonomous.
Curtis L. Wesley, Linda J. S. Allen
openaire   +3 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Mathematical model for the control of measles

open access: yesJournal of Applied Sciences and Environmental Management, 2018
We proposed a mathematical model of measles disease dynamics with vaccination by considering the total number of recovered individuals either from natural recovery or recovery due to vaccination.
O.J. Peter   +4 more
doaj   +1 more source

The Basic Reproduction Number as a Predictor for Epidemic Outbreaks in Temporal Networks

open access: yesPLOS ONE, 2015
The basic reproduction number R0 -- the number of individuals directly infected by an infectious person in an otherwise susceptible population -- is arguably the most widely used estimator of how severe an epidemic outbreak can be. This severity can be more directly measured as the fraction people infected once the outbreak is over, .
Holme, Petter, Masuda, Naoki
openaire   +8 more sources

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

Threshold dynamics of a periodic SIR model with delay in an infected compartment

open access: yesMathematical Biosciences and Engineering, 2014
Threshold dynamics of epidemic models in periodic environmentsattract more attention. But there are few papers which are concernedwith the case where the infected compartments satisfy a delaydifferential equation.
Zhenguo Bai
doaj   +1 more source

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