Results 101 to 110 of about 1,121,626 (305)

Models for the spread and persistence of hantavirus infection in rodents with direct and indirect transmission

open access: yesMathematical Biosciences and Engineering, 2009
Hantavirus, a zoonotic disease carried by wild rodents, is spread among rodents via direct contact and indirectly via infected rodent excreta in the soil.
Curtis L. Wesley   +2 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number

open access: yes, 2018
An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R 0 , is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a number of ...
Bulla, Ingo   +2 more
core  

Stochastic epidemic models: a survey [PDF]

open access: yes, 2009
This paper is a survey paper on stochastic epidemic models. A simple stochastic epidemic model is defined and exact and asymptotic model properties (relying on a large community) are presented.
Britton, Tom
core  

On the Dynamics of Dengue Virus type 2 with Residence Times and Vertical Transmission

open access: yes, 2016
A two-patch mathematical model of Dengue virus type 2 (DENV-2) that accounts for vectors' vertical transmission and between patches human dispersal is introduced. Dispersal is modeled via a Lagrangian approach.
Bichara, Derdei   +4 more
core   +2 more sources

Threshold dynamics of a periodic SIR model with delay in an infected compartment

open access: yesMathematical Biosciences and Engineering, 2014
Threshold dynamics of epidemic models in periodic environmentsattract more attention. But there are few papers which are concernedwith the case where the infected compartments satisfy a delaydifferential equation.
Zhenguo Bai
doaj   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

The basic reproduction number of vector-borne plant virus epidemics

open access: yesVirus Research, 2017
The basic reproduction number R0 is a key parameter in plant disease epidemiology, which largely determines whether or not an epidemic will occur in a plant population. The next generation matrix approach to deriving and calculating the basic reproduction number of a plant virus epidemic is described.
Van den Bosch, F, Jeger, MJ
openaire   +5 more sources

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