Results 101 to 110 of about 1,179,686 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The linear stability and basic reproduction numbers for autonomous FDEs

open access: yesDiscrete and Continuous Dynamical Systems - S, 2023
In this paper, we first prove the stability equivalence between a linear autonomous and cooperative functional differential equation (FDE) and its associated autonomous and cooperative system without time delay. Then we present the theory of basic reproduction number $\mathcal{R}_0$ for general autonomous FDEs.
openaire   +2 more sources

Basic Reproduction Numbers for a Class of Reaction-Diffusion Epidemic Models

open access: yesBulletin of Mathematical Biology, 2020
We study the basic reproduction numbers for a class of reaction-diffusion epidemic models that are developed from autonomous ODE systems. We present a general numerical framework to compute such basic reproduction numbers; meanwhile, the numerical formulation provides useful insight into their characterizations.
Yang, Chayu, Wang, Jin
openaire   +3 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

The basic reproduction number in epidemic models with periodic demographics

open access: yesJournal of Biological Dynamics, 2009
Patterns of contact in social behaviour and seasonality due to environmental influences often affect the spread and persistence of diseases. Models of epidemics with seasonality and patterns in the contact rate include time-periodic coefficients, making the systems nonautonomous.
Curtis L, Wesley, Linda J S, Allen
openaire   +2 more sources

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

The role of asymptomatic carriers on the dynamics of a lymphatic filariasis model incorporating control strategies

open access: yesResults in Control and Optimization
This study presents a mathematical model to investigate the patterns of transmission in lymphatic filariasis. The model considers chronic, acute, and asymptomatic individuals and integrates key control strategies.
Mussa A. Stephano   +2 more
doaj   +1 more source

A Dynamical Analysis on a Tumour Virotherapy Model with Standard Incident Rate [PDF]

open access: yes, 2017
This paper discusses a dynamical analysis on a model that governs the growth of tumour cell under a therapy by using oncolytic viruses, on the standard incident rate.
Ikawati, D. S. (Deasy)   +2 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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