Results 101 to 110 of about 1,511,149 (326)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Spatial dynamics and the basic reproduction number of the 1991–1997 Cholera epidemic in Peru

PLoS Neglected Tropical Diseases, 2020
After being cholera free for over 100 years, Peru experienced an unprecedented epidemic of Vibrio cholerae O1 that began in 1991 and generated multiple waves of disease over several years.
A. Smirnova, Natalie Sterrett, O. Mujica, C. Munayco, L. Suárez, C. Viboud, G. Chowell   +6 more
semanticscholar   +1 more source

Analisa Kestabilan Bebas Penyakit pada Penyebaran Demam Berdarah Menggunakan Model Host – Vector [PDF]

, 2015
Tujuan dari penelitian ini adalah membentuk model matematika demam berdarah dengan mengasumsikan setelah sembuh dari sakit, maka dapat kembali rentan terhadap penyakit, dalam hal ini dibatasi untuk dua serotype.
Binatari, Nikenasih, Ratna Sari, Eminugroho   +1 more
core  

On the Dynamics of Dengue Virus type 2 with Residence Times and Vertical Transmission

, 2016
A two-patch mathematical model of Dengue virus type 2 (DENV-2) that accounts for vectors' vertical transmission and between patches human dispersal is introduced. Dispersal is modeled via a Lagrangian approach.
Bichara, Derdei, Castillo-Chavez, Carlos, Holechek, Susan A., Murillo, Anarina L., Velazquez-Castro, Jorge   +4 more
core   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Global stability of a distributed delayed viral model with general incidence rate

Open Mathematics, 2018
In this paper, we discussed a infinitely distributed delayed viral infection model with nonlinear immune response and general incidence rate. We proved the existence and uniqueness of the equilibria.
Ávila-Vales Eric, Canul-Pech Abraham, Rivero-Esquivel Erika   +2 more
doaj   +1 more source

Mathematical Modeling for Hospitalization due to Temperature Variations [PDF]

International Journal of Mathematical, Engineering and Management Sciences, 2019
Sudden changes in temperature occur due to ecological disturbances which results into global warming, volcanic eruption, depletion of ozone layer etc. This has become a crucial environmental and social issue all over the world.
Nita H. Shah, Purvi M. Pandya, Moksha H. Satia, Foram A. Thakkar   +3 more
doaj   +1 more source

Computation of the basic reproduction numbers for reaction-diffusion epidemic models

Mathematical Biosciences and Engineering, 2023
<abstract><p>We consider a class of $ k $-dimensional reaction-diffusion epidemic models ($ k = 1, 2, \cdots $) that are developed from autonomous ODE systems. We present a computational approach for the calculation and analysis of their basic reproduction numbers.
Yang, Chayu, Wang, Jin
openaire   +3 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Modelling repeated epidemics with general infection kernels [PDF]

, 2004
An integral equation approach is taken to explore the characteristics of a general infectious disease in a homogeneous population. It is shown that the final size of the epidemic depends on the basic reproduction ratio for the infection and the ...
Mann, J., Roberts, M.
core