Results 1 to 10 of about 8,297,014 (304)
Cancer-associated fibroblasts: from basic science to anticancer therapy
Experimental and Molecular Medicine, 2023 Cancer-associated fibroblasts (CAFs), as a central component of the tumor microenvironment in primary and metastatic tumors, profoundly influence the behavior of cancer cells and are involved in cancer progression through extensive interactions with ...
Dakai Yang +3 more
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CDK4 and CDK6 kinases: From basic science to cancer therapy
Science, 2022 Description Targeting cyclin-dependent kinases Cyclin-dependent kinases (CDKs), in complex with their cyclin partners, modulate the transition through phases of the cell division cycle.
A. Fassl, Y. Geng, P. Sicinski
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Journal of Clinical Investigation, 2023 Introduction A study design with repeated measures data occurs when each experimental unit has multiple dependent variable observations collected at several time points.
L. Muhammad
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The Basic Science of Patient–Physician Communication: A Critical Scoping Review
Academic medicine : journal of the Association of American Medical Colleges, 2021 Purpose Strong verbal communication skills are essential for physicians. Despite a wealth of medical education research exploring communication skills training, learners struggle to become strong communicators.
J. Forsey +5 more
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A guide to cancer immunotherapy: from T cell basic science to clinical practice
Nature reviews. Immunology, 2020 The T lymphocyte, especially its capacity for antigen-directed cytotoxicity, has become a central focus for engaging the immune system in the fight against cancer.
A. Waldman, Jill M. Fritz, M. Lenardo
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A research agenda for malaria eradication: basic science and enabling technologies.
PLoS Medicine, 2011 Today's malaria control efforts are limited by our incomplete understanding of the biology of Plasmodium and of the complex relationships between human populations and the multiple species of mosquito and parasite.
malERA Consultative Group on Basic Science and Enabling Technologies
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Epilepsia, 2005 Gautam Ullal, Margaret Fahnestock, and Ronald RacineNeurons communicate with each other via chemical neurotransmitters that react with protein receptors. The most common of the excitatory neurotransmitters is glutamate, which reacts with a variety of different receptor subtypes. One of these subtypes (called the kainate receptor, because it responds to
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Remyelination in multiple sclerosis: from basic science to clinical translation.
Lancet Neurology, 2020 The treatment of multiple sclerosis has been transformed by the successful development of immunotherapies that efficiently reduce disease activity and related clinical relapses during the relapsing-remitting phase of the disease.
C. Lubetzki +4 more
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Weak Complexes of Sulfur Compounds with Halide Ligands
Sultan Qaboos University Journal for Science, 2000 This review summarizes the study of the formation of SO2 -X- , SOCl2 -X- , SOBr2 -X- , SO2 Cl2 -X- complexes (X- = Cl- , Br- , I- , and SCN- ) in pure and mixed solvents of acetonitrile and dimethylsulfoxide over the past 30 years.
Salama B. Salama, Saad Wasif
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COVID-19 and COPD: a narrative review of the basic science and clinical outcomes
European Respiratory Review, 2020 The 2019 coronavirus disease (COVID-19) pandemic is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Clinical outcomes, including mortality, are worse in males, older individuals and patients with comorbidities.
A. Higham +3 more
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