Results 121 to 130 of about 21,884 (318)
Molecular Oncology, EarlyView.Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti +8 more
wiley +1 more source
Cochlear detection of double-slip motion in cello bowing [PDF]
arXiv, 2018 A double-slip motion of a cello sound is investigated experimentally with a bowing machine and analyzed using a Finite-Difference Time Domain (FDTD) cochlear model. A double-slip sound is investigated. Here the sawtooth motion of normal bowing is basically present, but within each period the bow hair tears off the strings once more within the period ...
arxiv
The role of membrane depolarization in the contractile response of the rabbit basilar artery to 5‐hydroxytryptamine. [PDF]
, 1987 C J Garland
openalex +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Quantifying Cochlear Implant Users' Ability for Speaker Identification using CI Auditory Stimuli [PDF]
arXiv, 2019 Speaker recognition is a biometric modality that uses underlying speech information to determine the identity of the speaker. Speaker Identification (SID) under noisy conditions is one of the challenging topics in the field of speech processing, specifically when it comes to individuals with cochlear implants (CI).
arxiv
ELECTRICAL PROPERTIES OF SMOOTH MUSCLE CELL MEMBRANE AND NEUROMUSCULAR TRANSMISSION IN THE GUINEA‐PIG BASILAR ARTERY [PDF]
, 1981 Tsuyoshi Karashima, Hirosi Kuriyama
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Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Auditory Sparse Representation for Robust Speaker Recognition Based on Tensor Structure
EURASIP Journal on Audio, Speech, and Music Processing, 2008 This paper investigates the problem of speaker recognition in noisy conditions. A new approach called nonnegative tensor principal component analysis (NTPCA) with sparse constraint is proposed for speech feature extraction.
Liqing Zhang, Qiang Wu
doaj +1 more source
Laser interferometric measurements of basilar membrane vibrations in cats using a round window approach [PDF]
, 1981 Shyam M. Khanna, D. G. B. Leonard
openalex +1 more source
Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source