Results 191 to 200 of about 27,811 (329)
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Artificial Basilar Membranes: A Triboelectric‐Based Artificial Basilar Membrane to Mimic Cochlear Tonotopy (Adv. Healthcare Mater. 19/2016) [PDF]
Jongmoon Jang+3 more
openalex +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Power analysis of the basilar membrane in the cochlea by mechanical resonance [PDF]
M. Jimenéz Hernández
openalex +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
Effectiveness of active middle ear implant placement methods in pathological conditions: basilar membrane vibration simulation. [PDF]
Lee S, Motegi M, Koike T.
europepmc +1 more source
Temporal Suppression of Clicked-Evoked Otoacoustic Emissions and Basilar-Membrane Motion in Gerbils. [PDF]
Charaziak KK, Dong W, Shera CA.
europepmc +1 more source
Simulation of mechano-electrical transduction in the cochlea considering basilar membrane vibration and the ionic current of the inner hair cells [PDF]
Sinyoung Lee, Takuji KOIKE
openalex +1 more source