Results 71 to 80 of about 1,376,887 (358)

THE AGRICULTURE SECTOR AND ITS IMPACT ON SYRIA'S WATER BASINS BETWEEN 1980 -2010.

open access: yesEuropean Journal of Geography, 2023
In the Syrian Arab Republic, water has become progressively scarcer and the demand has exceeded the supply and the availability of extant resources. Syria is considered a country of limited water resources.
Firas ARRAF
doaj  

Coupling SDSM downscaling climate and WMS hydrologic models in Khansar basin for runoff prediction under future climate change conditions [PDF]

open access: yesکاوش‌های جغرافیایی مناطق بیابانی, 2018
In recent years downscaling models are increasingly used in predicting climate variables. One of the application of the downscaling general circulation model (GCM) is used to predict the hydrological watershed.
Mostafa Karimi, Mohamadreza Aref
doaj   +1 more source

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

Trophic Diversity in Duckweed: Mixotrophy, More Than the Sum of its Extremes

open access: yesAdvanced Science, EarlyView.
In the context of rising DOC in aquatic environments, mixotrophic duckweed may impact carbon cycling by acting as either a carbon sink, as they absorb CO2 through photosynthesis, or a carbon source, as they release CO2 through respiration of absorbed DOC, which depends on DOC concentration, light availability, temperature, and other environmental ...
Zuoliang Sun   +5 more
wiley   +1 more source

The Delaware River Basin: The Final Report & Environmental Impact Statement of the Level B Study [draft]

open access: yes, 1979
The objective of the study is to develop a plan for the management of the water resources of the basin by identifying policies, programs and projects in the areas of water conservation; water quality; water supply; flow maintenance; flood loss reduction;

core   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

open access: yesAdvanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu   +8 more
wiley   +1 more source

Beyond Molecular Determinism: State‐Convergent Polymerization as a Functional Design Principle Under Chemical Complexity

open access: yesAdvanced Science, EarlyView.
This work introduces state‐convergent polymerization (SCP), a polymerization framework in which chemically diverse reaction pathways converge toward a reproducible functional polymeric state rather than a defined molecular structure. Using melanin and polydopamine as exemplars, SCP explains how robust polymer functions emerge under chemical and ...
Seonki Hong
wiley   +1 more source

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

open access: yesAdvanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi   +4 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

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