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Expert Review of Pharmacoeconomics and Outcomes Research, 2018
This study aims to determine methodological variations in the event simulation approaches of published health economic decision models, in the field of obesity, and to investigate whether their predictiveness and validity were investigated via external event validation techniques, which investigate how well the model reproduces reality.A systematic ...
Bjoern Schwander +2 more
exaly +3 more sources
This study aims to determine methodological variations in the event simulation approaches of published health economic decision models, in the field of obesity, and to investigate whether their predictiveness and validity were investigated via external event validation techniques, which investigate how well the model reproduces reality.A systematic ...
Bjoern Schwander +2 more
exaly +3 more sources
European Journal of Pharmaceutics and Biopharmaceutics
Several population pharmacokinetic (PopPK) models of caffeine in preterm infants have been published, but the extrapolation of these models to facilitate model-informed precision dosing (MIPD) in clinical practice is uncertain. This study aimed to comprehensively evaluate their predictive performance using an external, independent dataset.Data used for
Hao-Ran, Dai +10 more
exaly +3 more sources
Several population pharmacokinetic (PopPK) models of caffeine in preterm infants have been published, but the extrapolation of these models to facilitate model-informed precision dosing (MIPD) in clinical practice is uncertain. This study aimed to comprehensively evaluate their predictive performance using an external, independent dataset.Data used for
Hao-Ran, Dai +10 more
exaly +3 more sources
External evaluation of published population pharmacokinetic models of polymyxin B
European Journal of Clinical Pharmacology, 2021Several population pharmacokinetics (popPK) models for polymyxin B have been constructed to optimize therapeutic regimens. However, their predictive performance remains unclear when extrapolated to different clinical centers. Therefore, this study aimed to evaluate the predictive ability of polymyxin B popPK models.A literature search was conducted ...
Ya-qian Li +10 more
openaire +2 more sources
Multilevel modeling: Presenting and publishing the results for internal and external constituents
New Directions for Institutional Research, 2012AbstractMultilevel modeling provides several advantages over traditional ordinary least squares regression analysis; however, reporting results to stakeholders can be challenging. This chapter identifies some useful principles for reporting results.
Gary R. Pike, Louis M. Rocconi
openaire +1 more source
Therapeutic Drug Monitoring, 2021
Background: The objective of this study was to perform an external evaluation of published linezolid population pharmacokinetic and pharmacodynamic models, to evaluate the predictive performance using an independent data set. Another aim was to offer an elegant environment for display and simulation of both the concentration ...
Chika, Ogami +5 more
openaire +2 more sources
Background: The objective of this study was to perform an external evaluation of published linezolid population pharmacokinetic and pharmacodynamic models, to evaluate the predictive performance using an independent data set. Another aim was to offer an elegant environment for display and simulation of both the concentration ...
Chika, Ogami +5 more
openaire +2 more sources