Results 1 to 10 of about 2,059 (111)
Population Pharmacokinetics of Primaquine in the Korean Population [PDF]
Pharmaceutics, 2021 While primaquine has long been used for malaria treatment, treatment failure is common. This study aims to develop a population pharmacokinetic model of primaquine and its metabolite, carboxyprimaquine, and examine factors influencing pharmacokinetic ...
Woo-Yul Lee +6 more
doaj +4 more sources
Population pharmacokinetics [PDF]
Vojnosanitetski Pregled, 2005 Milovanović Jasmina R. +1 more
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Pharmacokinetics and population pharmacokinetics in pediatric oncology [PDF]
Pediatric Blood & Cancer, 2019 AbstractPharmacokinetic research has become increasingly important in pediatric oncology as it can have direct clinical implications and is a crucial component in individualized medicine. Population pharmacokinetics has become a popular method especially in children, due to the potential for sparse sampling, flexible sampling times, computing of ...
Sebastiaan D.T. Sassen +3 more
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Population pharmacokinetics analysis in Lixoft Monolix softwares
Фармакокинетика и Фармакодинамика, 2022 The article has discussed a step-by-step algorithm for developing population pharmacokinetics models in the Lixoft Monolix software. Features of population pharmacokinetics study’s methodology have described.
A. I. Platova
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Population pharmacokinetics of pomalidomide [PDF]
The Journal of Clinical Pharmacology, 2015 AbstractA population pharmacokinetic (PPK) model of pomalidomide was developed and the influence of demographic and disease‐related covariates on PPK parameters was assessed based on data from 6 clinical trials of pomalidomide (dose range, 0.5–10 mg) in healthy participants (n = 96) and patients with multiple myeloma (MM; n = 144).
Li, Yan +5 more
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Pharmaceuticals, 2021 Understanding the pharmacokinetics parameter of colistin methanesulfonate sodium (CMS) and colistin is needed to optimize the dosage regimen in critically ill patients. However, there is a scarcity of pharmacokinetics parameters in this population.
Mohd Shafie Zabidi +4 more
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Review on Population Pharmacokinetics of Amikacin in Paediatrics
Journal of Pure and Applied Microbiology, 2022 Amikacin is an aminoglycoside antibiotic with a broad-spectrum bacterial coverage that is frequently utilized both as monotherapy and in combination with other antibiotics for severe bacterial infections in the paediatric population.
Keerthana Chandrasekar +4 more
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Population pharmacokinetics of exenatide [PDF]
British Journal of Clinical Pharmacology, 2016 AimThe aim of the present analysis was to develop a core population pharmacokinetic model for the pharmacokinetic properties of immediate‐release (IR) exenatide, which can be used in subsequent analyses of novel sustained‐release formulations.MethodsData from eight clinical trials, evaluating a wide range of doses and different administration routes ...
Cirincione, Brenda, Mager, Donald E.
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Population pharmacokinetics of olanzapine in children [PDF]
British Journal of Clinical Pharmacology, 2020 AimsThe aim of this study was to evaluate the population pharmacokinetics (PopPK) of olanzapine in children and devise a model‐informed paediatric dosing scheme.MethodsThe PopPK of olanzapine was characterized using opportunistically collected plasma samples from children receiving olanzapine per standard of care for any indication.
Anil R. Maharaj +12 more
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Experience and pharmacokinetics of Levetiracetam in Korean neonates with neonatal seizures [PDF]
Korean Journal of Pediatrics, 2017 PurposeThe aims of this study were to evaluate the safety and pharmacokinetics of levetiracetam (LEV) in neonates with seizures and to establish a population pharmacokinetics (PPK) model by using the software NONMEM.MethodsA retrospective analysis of 18 ...
Jae Won Shin +7 more
doaj +1 more source