Results 11 to 20 of about 112,978 (213)
Frontiers in Pharmacology, 2021 The aim of this study was to establish the population pharmacokinetics (PK) model of Vancomycin for Chinese pediatric patients which can extrapolate to whole age periods by bridging the published adult population PK model and the established pediatric ...
Kai Shen +8 more
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Scientific Reports, 2017 Identifying individual genetic variation in drug metabolism pathways is of importance not only in livestock, but also in humans in order to provide the ultimate goal of giving the right drug at the right dose at the right time.
Jeremy T. Howard +5 more
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Population Pharmacokinetics of CC-122
Clinical Pharmacology: Advances and Applications, 2021 Yiming Cheng,1 Jian Chen,2 Michael Pourdehnad,3 Simon Zhou,1 Yan Li1 1Clinical Pharmacology & Pharmacometrics, Bristol Myers Squibb, Summit, NJ, USA; 2Non-Clinical Research & Development, Bristol Myers Squibb, Summit, NJ, USA; 3Early Clinical ...
Cheng Y +4 more
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Pharmaceutics, 2023 Rivaroxaban has been widely used to prevent and treat various thromboembolic diseases for more than a decade. However, whether a lower dose of rivaroxaban is required for Asians is still debatable.
Xiao-Qin Liu +4 more
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Frontiers in Pharmacology, 2020 ObjectiveThe purposes of our study were to investigate the population pharmacokinetics of teicoplanin in Chinese children with different renal functions and to propose the appropriate dosing regimen for these pediatric patients.MethodsWe performed a ...
Liuliu Gao +9 more
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Population Pharmacokinetics of Vancomycin in Pregnant Women
Frontiers in Pharmacology, 2022 Objective: Vancomycin is a glycopeptide antibacterial indicated for serious gram-positive infections. Pharmacokinetics (PK) of vancomycin have not been described in pregnant women.
Rahul K. Goyal +4 more
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DOXYCYCLINE PHARMACOKINETICS IN MAMMALIAN SPECIES OF VETERINARY INTEREST – AN OVERVIEW
Bulgarian Journal of Veterinary Medicine, 2022 Doxycycline is a broad-spectrum tetracycline antibiotic widely used in veterinary medicine. The current review aims to summarise the available data about pharmacokinetics in mammalian species of veterinary interest and to indicate the basic strategies ...
R. Mileva, A. Milanova
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PKPy: a Python-based framework for automated population pharmacokinetic analysis [PDF]
PeerJWe present PKPy, an open-source Python framework designed to automate population pharmacokinetic analysis workflows. The framework emphasizes user accessibility by minimizing the need for manual parameter initialization while maintaining analytical rigor.
Hyunseung Kong +2 more
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The influence of CYP2C8*3 on carbamazepine serum concentration in epileptic pediatric patients
Balkan Journal of Medical Genetics, 2016 The aim of the present study was to investigate the distribution of CYP2C8 variants *3 and *5, as well as their effect on carbamazepine pharmacokinetic properties, in 40 epileptic pediatric patients on carbamazepine treatment.
Milovanovic DD +7 more
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Pharmacokinetic Models of Tafenoquine: Insights for Optimal Malaria Treatment Strategies
PharmaceuticsTafenoquine (TQ) is a new 8-aminoquinoline antimalarial drug developed by the US Army for Plasmodium vivax malaria treatment. Modeling and simulation are essential tools for drug development and improving rationality in pharmacotherapy, and different ...
Luisa Oliveira Santos +2 more
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