Results 31 to 40 of about 5,010 (209)

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source

External validation of population pharmacokinetic models for meropenem in critically ill adult patients

Journal of Global Antimicrobial Resistance
Background: While several meropenem population pharmacokinetic (popPK) models have been developed, few have undergone external validation, a crucial step to confirm their robustness and applicability in real-world settings. Objective: This study aimed to
Carla Bastida, Alba Escolà-Rodríguez, Sara Fernández, Pedro Castro, Dolors Soy   +4 more
doaj   +1 more source

Transferability of Published Population Pharmacokinetic Models for Apixaban and Rivaroxaban to Subjects with Obesity Treated for Venous Thromboembolism: A Systematic Review and External Evaluations

Pharmaceutics, 2023
Apixaban and rivaroxaban have first-line use for many patients needing anticoagulation for venous thromboembolism (VTE). The pharmacokinetics of these drugs in non-obese subjects have been extensively studied, and, while changes in pharmacokinetics have ...
Cyril Leven, Pauline Ménard, Isabelle Gouin-Thibault, Alice Ballerie, Karine Lacut, Edouard Ollier, Jérémie Théreaux   +6 more
doaj   +1 more source

Survival by Race and Ethnicity in Children and Adolescents/Young Adults With Relapsed/Refractory Hodgkin Lymphoma: A Pooled Analysis of Children's Oncology Group Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Despite 5‐year survival rates of over 90% among children and adolescents/young adults (CAYAs) with classic Hodgkin lymphoma (cHL), 15%–20% relapse after frontline therapy. Prior analysis of frontline Children's Oncology Group (COG) clinical trials demonstrated that, despite similar rates of relapse, non‐Hispanic Black (NHB) and ...
Mallorie B. Heneghan, Lindsay A. Renfro, Yue Wu, Katia M. Crisler, Erin Marcotte, Tanya Trippett, Terzah Horton, Bradford S. Hoppe, Frank G. Keller, Chris Forlenza, Cindy Schwartz, Kara M. Kelly, Peter D. Cole, Sharon M. Castellino, Justine M. Kahn   +14 more
wiley   +1 more source

External evaluation of a published population pharmacokinetic model of valproic acid in Thai manic patients

European Journal of Hospital Pharmacy, 2018
To evaluate external predictability of a population pharmacokinetic model of valproic acid in Thai patients with mania to ensure its appropriateness for use in other clinical settings.The published population pharmacokinetic model was evaluated for its predictive ability (at both individual and population levels) and its precision by means of mean ...
Janthima Methaneethorn, Manupat Lohitnavy   +1 more
openaire   +3 more sources

Meta-research: How many diagnostic or prognostic models published in radiological journals are evaluated externally?

European Radiology, 2023
Abstract Objectives Prognostic and diagnostic models must work in their intended clinical setting, proven via “external evaluation”, preferably by authors uninvolved with model development. By systematic review, we determined the proportion of models published in high-impact radiological journals that are evaluated ...
Maira Hameed, Jason Yeung, Darren Boone, Sue Mallett, Steve Halligan   +4 more
openaire   +3 more sources

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Reply to Dolu, K.O. Comment on “Topaloglu et al. Machine Learning-Driven Lung Sound Analysis: Novel Methodology for Asthma Diagnosis. Adv. Respir. Med. 2025, 93, 32”

Advances in Respiratory Medicine
Thank you for forwarding the external comment regarding our published article (Machine Learning-Driven Lung Sound Analysis: Novel Methodology for Asthma Diagnosis) [...]
Ihsan Topaloglu, Gulfem Ozduygu, Cagri Atasoy, Guntug Batıhan, Damla Serce, Gulsah Inanc, Mutlu Onur Güçsav, Arif Metehan Yıldız, Turker Tuncer, Sengul Dogan, Prabal Datta Barua   +10 more
doaj   +1 more source

Management of External Parasites with Forced-Use Dust Bags

EDIS, 2009
Revised! ENY-281, a 7-page illustrated fact sheet by P. E. Kaufman, P. G. Koehler, and J. F. Butler, describes this safe, economical, and effective technique for managing external parasites on cattle in Florida — background, directions for hanging ...
Phillip E. Kaufman, Philip G. Koehler, Jerry F. Butler   +2 more
doaj   +1 more source