Results 51 to 60 of about 1,420,968 (272)

Meta-research: How many diagnostic or prognostic models published in radiological journals are evaluated externally?

European Radiology, 2023
Abstract Objectives Prognostic and diagnostic models must work in their intended clinical setting, proven via “external evaluation”, preferably by authors uninvolved with model development. By systematic review, we determined the proportion of models published in high-impact radiological journals that are evaluated ...
Maira Hameed, Jason Yeung, Darren Boone, Sue Mallett, Steve Halligan   +4 more
openaire   +3 more sources

Knowledge management at the National Oceanography Centre: perspectives from an information specialist

, 2010
No abstracts are to be cited without prior reference to the author.The National Oceanography Centre (NOC) is a newly established, national research organization, delivering world-class integrated marine science and technology from the coast to the deep ...
Jane Stephenson (17910302)
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Internal, external, and ecological validity in research design, conduct, and evaluation

Indian Journal of Psychological Medicine, 2018
Reliability and validity describe desirable psychometric characteristics of research instruments. The concept of validity is also applied to research studies and their findings.
Chittaranjan Andrade
doaj   +1 more source

Costs and benefits of reducing air pollutant emissions as a result of bringing coal and lignite-fired power plants into compliance with BAT LCP conclusions

Environmental Protection and Natural Resources, 2023
The analysis carried out regarding the costs of adapting to the best available technique (BAT) conclusions in relation to the benefits achieved (external costs) showed that these benefits significantly exceed the cost of investments necessary to meet the
Lewandowski Janusz, Melka Krzysztof, Dubel Anna, Kłeczek Maria   +3 more
doaj   +1 more source

External evaluation of a published population pharmacokinetic model of valproic acid in Thai manic patients

European Journal of Hospital Pharmacy, 2018
To evaluate external predictability of a population pharmacokinetic model of valproic acid in Thai patients with mania to ensure its appropriateness for use in other clinical settings.The published population pharmacokinetic model was evaluated for its predictive ability (at both individual and population levels) and its precision by means of mean ...
Janthima Methaneethorn, Manupat Lohitnavy   +1 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

What types of unintentional injuries kill our children? Do infants die of the same types of injuries? A systematic review

Clinics
The objective of this study was to review mortality from external causes (accidental injury) in children and adolescents in systematically selected journals.
Janete Honda Imamura, Eduardo Juan Troster, Carlos Augusto Cardim de Oliveira   +2 more
doaj   +1 more source

Analysis of MRI and CT-based radiomics features for personalized treatment in locally advanced rectal cancer and external validation of published radiomics models

Scientific Reports, 2022
Radiomics analyses commonly apply imaging features of different complexity for the prediction of the endpoint of interest. However, the prognostic value of each feature class is generally unclear.
Iram Shahzadi, Alex Zwanenburg, Annika Lattermann, Annett Linge, Christian Baldus, Jan C. Peeken, Stephanie E. Combs, Markus Diefenhardt, Claus Rödel, Simon Kirste, Anca-Ligia Grosu, Michael Baumann, Mechthild Krause, Esther G. C. Troost, Steffen Löck   +14 more
doaj   +1 more source

Does Preexisting Antiplatelet Treatment Influence Postthrombolysis Intracranial Hemorrhage in Community‐treated Ischemic Stroke Patients? An Observational Study [PDF]

, 2013
Objectives Intracranial hemorrhage ( ICH ) after acute stroke thrombolysis is associated with poor outcomes. Previous investigations of the relationship between preexisting antiplatelet use and the safety of intravenous ( IV ) thrombolysis have been ...
O'Neil, Brian J., Kade, Allison M., Kalbfleisch, Jack, Scott, Phillip A., Kwok, Heemun, Adelman, Eric E., Frederiksen, Shirley M., Skolarus, Lesli E., Meurer, William J.   +8 more
core   +1 more source