Results 91 to 100 of about 8,045,847 (325)

Role of base‐backbone and base‐base interactions in alternating DNA conformations

FEBS Letters, 1996
Sequence‐specific conformational differences between dinucleotide steps are characterised using published crystal coordinates with special attention to steric hindrance of the methyl group of a T base to the neighbouring base, and, more importantly, to the sugar‐phosphate backbone. The TT step is inflexible and B‐like, as it has two methyl groups which
Masashi Suzuki, Naoto Yagi, John T. Finch   +2 more
openaire   +3 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Semi-classical Theory of Conductance and Noise in Open Chaotic Cavities

, 1999
Conductance and shot noise of an open cavity with diffusive boundary scattering are calculated within the Boltzmann-Langevin approach. In particular, conductance contains a non-universal geometric contribution, originating from the presence of open ...
B. L. Altshuler, B. L. Altshuler, C. W. J. Beenakker, C. W. J. Beenakker, E. Cuevas, E. Louis, E. V. Sukhorukov, E. V. Sukhorukov, E. V. Sukhorukov, H. U. Baranger, J. A. Vergés, K. E. Nagaev, M. J. M. de Jong, M. J. M. de Jong, M. Lax, P. W. Brouwer, R. A. Jalabert, R. Landauer, S. A. van Langen, S. V. Gantsevich, Sh. M. Kogan, Sh. M. Kogan, V. I. Okulov, V. I. Okulov, V. Tripathi, Y. B. Levinson, Y. V. Fyodorov, Ya. M. Blanter, Ya. M. Blanter, Ya. M. Blanter, Yu. V. Nazarov, Yu. V. Nazarov   +31 more
core   +2 more sources

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Anesthetic Management of a Neonate with Subdural Hematoma

Journal of Neuroanaesthesiology and Critical Care, 2021
Jili Basing, Ashish Bindra, Niraj Kumar
doaj   +1 more source

Quasiclassical and Quantum Systems of Angular Momentum. Part II. Quantum Mechanics on Lie Groups and Methods of Group Algebras [PDF]

, 2010
In Part I of this series we presented the general ideas of applying group-algebraic methods for describing quantum systems. The treatment was there very "ascetic" in that only the structure of a locally compact topological group was used.
Gołubowska, B., Kovalchuk, V., Martens, A., Rożko, E. E., Sławianowski, J. J.   +4 more
core  

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

The influence of basing conditions on the precision of parts treated by the deforming broaching [PDF]

, 2014
Розглянуто науково-технічні питання зі впливу умов базування на точність виробів, оброблених деформуючим протягуванням та з розроблення технологічних методів її забезпечення.
Nemirovsky, Ya.
core  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source