Results 101 to 110 of about 34,952,696 (369)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

The influence of basing conditions on the precision of parts treated by the deforming broaching [PDF]

open access: yes, 2014
Розглянуто науково-технічні питання зі впливу умов базування на точність виробів, оброблених деформуючим протягуванням та з розроблення технологічних методів її забезпечення.
Nemirovsky, Ya.
core  

Justice and the Politics of Difference

open access: yesThe New Social Theory Reader, 1990
This book challenges the prevailing philosophical reduction of social justice to distributive justice. It critically analyzes basic concepts underlying most theories of justice, including impartiality, formal equality, and the unitary moral subjectivity.
I. Young
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

The New Features of Landslide Relief Discovered Using Lidar – Case Study from Babia Góra Massif, Western Carpathian Mountains

open access: yesQuaestiones Geographicae, 2014
Basing on LiDAR data, the re-interpretation of the limit and distribution of the selected landslide forms in 9 test areas were carried out. The forms are located at the slopes of the monoclinal ridge of Babia Góra Mt.
Łajczak Adam   +2 more
doaj   +1 more source

Basing Respiratory Management of COVID-19 on Physiological Principles

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2020
M. Tobin
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

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