Results 281 to 290 of about 8,420,667 (325)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Editorial: Cell structure and dynamics in the nematode <i>Caenorhabditis elegans</i>. [PDF]

Front Cell Dev Biol
Mierke CT.
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Role of fine needle aspiration biopsy in the diagnosis of pleomorphic adenoma. [PDF]

Acta Otorhinolaryngol Ital
Tropiano P, Rizzo D, Mele DA, Manca A, Bella MA, Deiana A, Crescio C, Varrucciu S, Mureddu L, Calò L, Tiana CR, Gallus R, Cossu A, Galli J, Bussu F.   +14 more
europepmc   +1 more source

Assessment of combined serum sST2 and AFP levels in the diagnosis of hepatocellular carcinoma. [PDF]

PeerJ
Tang X, Wang D, Ding T, Lin R, He M, Wang R, Li L.   +6 more
europepmc   +1 more source

Pathomics-based machine learning models for predicting pathological complete response and prognosis in locally advanced rectal cancer patients post-neoadjuvant chemoradiotherapy: insights from two independent institutional studies. [PDF]

BMC Cancer
Zhang Y, Huang Y, Xu M, Zhuang J, Zhou Z, Zheng S, Zhu B, Guan G, Chen H, Liu X.   +9 more
europepmc   +1 more source

Integrating genetic insights into pain management and opioid use optimization in chronic pain and substance abuse populations. [PDF]

Explor Res Clin Soc Pharm
Jairoun AA, Al-Hemyari SS, Shahwan M, Al-Ghananeem AM, Alnuaimi GR, Porntaveetus T.   +5 more
europepmc   +1 more source

The Management Modality of Aseptic Loosening for Acetabular Components Along With Femur Prostheses Following Primary Hip Arthroplasty: A Reports of Four Cases. [PDF]

Int Med Case Rep J
Zhu H, Fu L, Xie Y, Yuan X, Chen S, Xie L.   +5 more
europepmc   +1 more source

Partial intraoperative signal recovery is associated with normal postoperative vocal cord motility in patients with intraoperative loss of signal. [PDF]

Updates Surg
Gallucci P, Procopio PF, Pennestrì F, Marincola G, D'Alatri L, Martullo A, De Crea C, Raffaelli M.   +7 more
europepmc   +1 more source