Navigating Oral Food Challenges in Clinical Trials to Keep the Science Moving Forward
ABSTRACT The oral food challenge (OFC) has long been the reference standard for food allergy diagnosis, as well as to confirm natural development of oral tolerance. The utilization of OFCs has significantly broadened from its role in defining disease to defining participant eligibility, individual allergen reactivity thresholds and treatment outcomes ...
Edwin H. Kim +10 more
wiley +1 more source
Hypersensitivity to Excipients in Drugs: An EAACI Position Paper
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey +10 more
wiley +1 more source
Exploring fundus‐controlled mesopic and scotopic perimetry in inherited retinal disease
Abstract Purpose Microperimetry is increasingly used as an outcome measure in clinical trials for retinal disease. This study compares mesopic and scotopic microperimetry in a heterogeneous cohort of patients with inherited retinal disease to assess their suitability as clinical trial outcome measures and to determine the most appropriate testing ...
Laura J. Taylor +4 more
wiley +1 more source
Application of Multi‐Method Dating for Understanding the Gravettian North of Moravia, Central Europe
ABSTRACT This article presents the results of integrating three methods to assess the age of the Upper Palaeolithic site of Pietraszyn 11 (SW Poland), close to the Moravian Gate. Sediment chronology determined using optically stimulated luminescence produced promising, yet ambiguous results (51.0 ± 3.7 to 20.3 ± 0.7 ka).
A. Wiśniewski +16 more
wiley +1 more source
Abstract As students learn and practice new skills in university courses, their behaviour can change in response to competing demands and increasing content complexity. However, most metrics used to evaluate study behaviour focus on the number or sequence of activities rather than on the change of behaviour.
Oleksandra Poquet +2 more
wiley +1 more source
Gaussian Quantum Bat Algorithm with Direction of Mean Best Position for Numerical Function Optimization. [PDF]
Huang X, Li C, Pu Y, He B.
europepmc +1 more source
Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov +15 more
wiley +1 more source
Improved Bat Algorithm Based on Multipopulation Strategy of Island Model for Solving Global Function Optimization Problem. [PDF]
Guo SS, Wang JS, Ma XX.
europepmc +1 more source
From Inaction to Action: The Cognitive Liberation of Amazon Workers in North Carolina
ABSTRACT We examine the mechanism by which workers move from inaction to collective action, focusing on cognitive liberation, the awareness that change is possible, as it unfolded among workers at an Amazon warehouse in North Carolina who contributed to the emergence of an independent, worker‐led union during a period of renewed growth in organising ...
Carla Lima Aranzaes, Destiny Blackwell
wiley +1 more source
Reporting cell planning-based cellular mobility management using a Binary Artificial Bat algorithm. [PDF]
Swayamsiddha S +4 more
europepmc +1 more source

