ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin +16 more
wiley +1 more source
Preparation, Characterization, and Adsorption Performance of an Interlayer-Expanded PPy/Maghnite-Cu<sup>2+</sup> Nanocomposite for Methylene Blue Removal. [PDF]
Bekhti MA +6 more
europepmc +1 more source
Synaptic κ‐Ga2O3 Photodetectors for Privacy‐Enhancing Neuromorphic Computing
We report on a single‐element neuromorphic sensor based on the persistent photoconductivity (PPC) of κ‐phase Ga2O3 capable of sensing ultraviolet light and harnessing intrinsic data privacy. The approach establishes a materials‐enabled pathway toward compact, intelligent, and privacy‐enhancing optoelectronic hardware for next‐generation edge systems ...
Yanqing Jia +13 more
wiley +1 more source
Synthesis of Glycerin Carbonate by an Environmentally Friendly Novel Catalytic Membrane of Poly(vinyl alcohol)/Deep Eutectic Solvent. [PDF]
Hasirci G, Durmaz Hilmioglu N.
europepmc +1 more source
Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng +5 more
wiley +1 more source
Revealing the pH-Dependent Adsorption Dynamics of Tetracycline Hydrochloride on Phosphoric Acid-Activated Corncob Biochar. [PDF]
Zhao Q +9 more
europepmc +1 more source
DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout
A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li +12 more
wiley +1 more source
The Structure-Activity Relationship and Anticoagulation Mechanism of Polyglycerol Sulfates of Different Architectures. [PDF]
Krage C +6 more
europepmc +1 more source
The ZnSm‐Cl dinuclear molecular complex was synthesized through a simple one‐pot method. ZnL and Sm3+ exhibit complementary temperature‐dependent emission As the temperature increases, a noticeable color difference of ZnSm‐Cl can be observed within the room temperature range of 253‐333 K.
Ye Xia +7 more
wiley +1 more source
Sorption properties of several polyethersulfone membranes for hydrophilic and hydrophobic emerging contaminants: implications for their application in passive sampling. [PDF]
Scapuzzi C +4 more
europepmc +1 more source

