Results 221 to 230 of about 154,933 (276)

Identification of a novel signature in progression of non-small cell lung cancer based on HdWGCNA and in vitro validation. [PDF]

BMC Med Genomics
Zhang K, Xia W, Li Y, Shi B, Yang W.
europepmc   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Deep-Learning Tool ScVital Enables Species-Agnostic Integration of Cancer Cell States. [PDF]

Cancer Res
Rub J, Chan JE, Sussman C, Guzman G, Tap WD, Antonescu CR, Singer S, Tammela T, Betel D.   +8 more
europepmc   +1 more source

Panomics Integration via Machine Learning Prioritizes TAF1D as a Therapeutic Vulnerability in Lung Adenocarcinoma. [PDF]

Hum Mutat
Ding L, Xu Q, Liu D, Wu J, Cai X, Xu F, Ma S, Wang H, Shi Y.   +8 more
europepmc   +1 more source

Concordant and Discordant Transcriptomic Signatures of Twin Placentas in the Setting of Preeclampsia. [PDF]

Hypertension
Ackerman WE, Buhimschi IA, Jing H, Brown TL, Zhao G, Buhimschi CS.   +5 more
europepmc   +1 more source

Artificial neural network-based immune biomarker signature predicts pathological complete response to neoadjuvant chemotherapy in HER2-negative breast cancer. [PDF]

Front Oncol
Zhang Y, Nong S, Deng S, Su Q, Lu J, Fang D, Qin S, Ma Y.   +7 more
europepmc   +1 more source

Same-Slide Spatial Multi-Omics Integration with IN-DEPTH Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor Microenvironment. [PDF]

Cancer Discov
Yiu SPT, Chang Y, Yeo YY, Qiu H, Wu W, Michel HA, Jin X, Huang R, Kure S, Parmelee L, Luo S, Cramer P, Lee JL, Wang Y, Zhao Z, Yeung J, El Ahmar N, Simsek B, Mohanna R, Van Orden M, Lu WS, Livak KJ, Li S, Gao C, Burgess M, Keane C, Shahryari J, Kingsley LG, Al-Humadi RN, Nasr S, Nkosi D, Sadigh S, Rock P, Frauenfeld L, Kaufmann L, Zhu B, Basak A, Dhanikonda N, Chan CN, Krull J, Cho YW, Chen CY, Brown J, Wang H, Zhao B, Lee JJ, Loo LH, Kim DM, Boussiotis VA, Zhang B, Wei K, Shalek AK, Howitt BE, Signoretti S, Schürch CM, Hodi FS, Burack WR, Rodig SJ, Ma Q, Jiang S.   +59 more
europepmc   +1 more source

Alterations to the bronchial gene-expression effects of tobacco smoking in people living with HIV. [PDF]

J Acquir Immune Defic Syndr
Lee M, Olson A, Pickering RT, Ieong MH, Kivett D, Roche S, Xiao X, Liu G, Asundi A, Lin NH, Lenburg ME.   +10 more
europepmc   +1 more source