Results 61 to 70 of about 7,515 (307)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Batching CSIDH Group Actions using AVX-512
Transactions on Cryptographic Hardware and Embedded Systems, 2021 Commutative Supersingular Isogeny Diffie-Hellman (or CSIDH for short) is a recently-proposed post-quantum key establishment scheme that belongs to the family of isogeny-based cryptosystems.
Hao Cheng +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Accuracy Enhancement of Automated System for Multicomponent Batching of Bulk Materials
MATEC Web of Conferences, 2015 In the paper the choice of reasonable structure of automated system for multicomponent batching of bulk materials has been substantiated to minimize the batching error of about 3% in case the recipe mixture includes small components of big importance in ...
Bukreev V.G. +2 more
doaj +1 more source
Batch Coloring of Graphs [PDF]
Algorithmica, 2017 In graph coloring problems, the goal is to assign a positive integer color to each vertex of an input graph such that adjacent vertices do not receive the same color assignment. For classic graph coloring, the goal is to minimize the maximum color used, and for the sum coloring problem, the goal is to minimize the sum of colors assigned to all input ...
Joan Boyar +4 more
openaire +5 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Simulated annealing approach for optimal batching in a warehouse
, 2022 Order-picking in a warehouse is normally the most expensive operation as it takes the longest time. In conjunction with this, order batching is introduced to expedite the orders for the picking process.
Ahmad, Norulhusna +3 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Implementation of a laboratory batching procedure with a correction for fines and moisture
Infraestructura Vial, 2016 The selection of an appropriate aggregate structure is a key step during mix design since this directly affects mix performance and the amount of asphalt in the mix.
Jose Corrales Azofeifa +1 more
doaj +1 more source