Results 31 to 40 of about 675,712 (305)
BMJ Open, 2023 Objective Explore the experiences of patients and clinicians in rheumatology and cardiology outpatient clinics during the first year of the COVID-19 pandemic, focusing on the impact of remote consultations on interpersonal dynamics.Design Qualitative ...
Raj Sengupta +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Elite sport and education support systems : a case study of the Team Bath Judo Programme at the University of Bath [PDF]
, 2008 High level sport is linked to educational institutions. Historically, a number of systems designed to develop high level sports performance have been based at places of learning.
Callan, Michael
core
Influence of Ultrasonic Bath on Mold-Assisted Electrodeposition of Gold Microelectrode Arrays
ProceedingsThis study investigates the potential of ultrasonic baths to enhance mold-assisted electrodeposition for fabricating three-dimensional (3D) microelectrode arrays (MEAs) with improved quality and reliability.
Neeraj Yadav +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Bath Workhouse Burial Ground: walking the names [PDF]
, 2020 As you walk in this space, listen….. Below your feet are the bodies of more than 3000 people who died of poverty in the Bath Union Workhouse between 1858 and 1899.
White, R
core
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Bath anti-mapper: a co-creation tactic [PDF]
, 2017 Developing co-creation tactics walking and sensing the silences, gaps and distortions in the official version of the City. A hosted performative walk and workshop presented for the Co-Creation Network as part of the First International Co-Creation ...
White, R
core
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source