Results 41 to 50 of about 257,472 (267)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Historika : Studi di Storia Greca e Romana, 2013 CIL, V 5136 da Bergomum costituisce un'interessante testimonianza dell'evergetismo architettonico-termale in area transpadana. L'iscrizione evidenzia la concezione di un evergetismo privato improntato a criteri di pubblica utilità e prova il valore dell'
Paola Tomasi
doaj +1 more source
Avian Assemblages at Bird Baths: A Comparison of Urban and Rural Bird Baths in Australia. [PDF]
PLoS ONE, 2016 Private gardens provide habitat and resources for many birds living in human-dominated landscapes. While wild bird feeding is recognised as one of the most popular forms of human-wildlife interaction, almost nothing is known about the use of bird baths ...
Gráinne P Cleary +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Nonequilibrium thermal entanglement in three-qubit $XX$ model
, 2009 Making use of the master equation and effective Hamiltonian approach, we investigate the steady state entanglement in a three-qubit $XX$ model. Both symmetric and nonsymmetric qubit-qubit couplings are considered. The system (the three qubits) is coupled
D. F. Walls +6 more
core +1 more source
The maximum efficiency of nano heat engines depends on more than temperature [PDF]
, 2019 Sadi Carnot's theorem regarding the maximum efficiency of heat engines is considered to be of fundamental importance in thermodynamics. This theorem famously states that the maximum efficiency depends only on the temperature of the heat baths used by the
Ng, Nelly +2 more
core +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Strange Heat Flux in (An)Harmonic Networks
, 2003 We study the heat transport in systems of coupled oscillators driven out of equilibrium by Gaussian heat baths. We illustrate with a few examples that such systems can exhibit ``strange'' transport phenomena. In particular, {\em circulation} of heat flux
Eckmann, Jean-Pierre, Zabey, Emmanuel
core +2 more sources
Weak coupling study of decoherence of a qubit in disordered magnetic environments [PDF]
, 2009 We study the decoherence of a qubit weakly coupled to frustrated spin baths. We focus on spin-baths described by the classical Ising spin glass and the quantum random transverse Ising model which are known to have complex thermodynamic phase diagrams as ...
Chitra, R. +2 more
core +2 more sources
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source