Involment of p53, Bax, and Bcl-2 Pathway in Microcystins-Induced Apoptosis in Rat Testis
It has been reported that microcystins (MCs) could accumulate in the gonads of mammals and MCs exposure exerts obvious toxic effects on male reproductive system of mammals.
xieping@ihb.ac.cn +7 more
core
目的观察凋亡基因Bcl-2、Bax在糖尿病大鼠脑缺血再灌注海马CA1区神经元损伤中的表达。方法采用链脲佐菌素(STZ)诱导和线栓法制备糖尿病大脑中动脉闭塞模型(MCAO),应用HE染色和免疫组化方法比较糖尿病脑缺血再灌注组与缺血再灌注组海马CA1区神经元缺失、凋亡基因Bcl-2、Bax的表达。结果糖尿病脑缺血再灌注组海马CA1区神经元缺失,明显高于缺血再灌注组 ...
张季声 +7 more
doaj
Aim. To determine unbalance in the system of programmed cell death in the cells CD34+ of the bone marrow (BM) and peripheral blood (PB) before and after cytostatic impact in acute leukemia (AL). Material and methods.
Elena Evgen'evna Khodunova +11 more
doaj
Cycloastragenol Attenuates Cisplatin-Induced Ovarian Toxicity in Rats: Associations With TERT Expression, Apoptotic Balance, and FOXO3a-mTOR-Related Signaling. [PDF]
Erol GNA, Yar AS, Kaplanoğlu GT.
europepmc +1 more source
Luteolin Alleviates Axitinib-Induced Cardiomyocyte Apoptosis in Mice. [PDF]
Ji SW +5 more
europepmc +1 more source
Elucidation of Selective Apoptosis of Breast Cancer Cells Induced by <i>Panax ginseng</i>-Derived Exosomes via Regulation of Bax/Bcl-2 Ratio and AMPK-<i>α</i> Signaling. [PDF]
Han MH +5 more
europepmc +1 more source
IFI27 and BAX are Essential for GSDME-Mediated Myeloma Cell Pyroptosis. [PDF]
Cui Y +12 more
europepmc +1 more source
Hypotonicity-Induced WNK1 Phosphorylation Prevents H<sub>2</sub>O<sub>2</sub>-Induced Apoptosis in Vascular Smooth Muscle Cells. [PDF]
Zhang Y +11 more
europepmc +1 more source
Dissecting the mechanisms of pro-apoptotic BAX modulation
Apoptosis plays a critical role in maintaining normal tissue homoeostasis in multicellular organisms. Deregulation of apoptosis can contribute to diseases such as cancer.
Uchime, Onyinyechukwu
core

