Results 1 to 10 of about 112,671,011 (290)

RELATIONSHIP BETWEEN APOPTOSIS MARKERS(P53, BCL-2, BAX) AND CLINICAL-MORPHOLOGICAL PARAMETERS AND SURVIVAL IN NON-SMALL CELL LUNG CANCER

Сибирский онкологический журнал, 2016
The purpose of the study was to analyze the relationship between expression of the р53, bcl-2 and bax genes and clinical-morphological parameters and survival in patients with non-small cell lung cancer (NSCLC).
D. S. Kobyakov, А. F. Lazarev, Е. L. Lushnikova, L. M. Nepomnyashchikh   +3 more
doaj  

Bcl-2 dependent modulation of Hippo pathway in cancer cells

Cell Communication and Signaling
Introduction Bcl-2 and Bcl-xL are the most studied anti-apoptotic members of Bcl-2 family proteins. We previously characterized both of them, not only for their role in regulating apoptosis and resistance to therapy in cancer cells, but also for their ...
Simona D’Aguanno, Matteo Brignone, Stefano Scalera, Martina Chiacchiarini, Marta Di Martile, Elisabetta Valentini, Francesca De Nicola, Alessia Ricci, Fabio Pelle, Claudio Botti, Marcello Maugeri-Saccà, Donatella Del Bufalo   +11 more
doaj   +1 more source

Grape Stem Extracts from Vitis vinifera cv. Areni Noir and cv. Rkatsiteli: Rkatsiteli Shows Stronger Antiproliferative Activity and Drives BCL-2/p53-Mediated Apoptosis in MCF-7 Breast Cancer Cells [PDF]

Virab Kirakosyan, Hayarpi Javrushyan, Armenuhi Mnatsakanyan, Astghik Mkrtchyan, Andranik M. Davinyan, Serkos A. Haroutounian, Nikolay V. Avtandilyan   +6 more
openalex   +1 more source

Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL

Nature Communications
Overexpression of BCL-xL and BCL-2 play key roles in tumorigenesis and cancer drug resistance. Advances in PROTAC technology facilitated recent development of the first BCL-xL/BCL-2 dual degrader, 753b, a VHL-based degrader with improved potency and ...
Digant Nayak, Dongwen Lv, Yaxia Yuan, Peiyi Zhang, Wanyi Hu, Anindita Nayak, Eliza A. Ruben, Zongyang Lv, Patrick Sung, Robert Hromas, Guangrong Zheng, Daohong Zhou, Shaun K. Olsen   +12 more
doaj   +1 more source

Immunohistochemical Markers and Post‐Mortem Interval Estimation: A Proof‐Of‐Concept Study on Immunoexpression of Caspase‐8, Annexin A1, Bcl‐2, and NF‐κB in Autoptic Tissues [PDF]

Nicola Pigaiani, Stefano Gobbo, Vito Cirielli, Barbara Oliviero, Marianna Garavello, Enrico Ambrosi, Francesco Ausania, Serena Ammendola, Federica Bortolotti, Matteo Brunelli   +9 more
openalex   +1 more source

Assessment of BCL ‐2 expression in bone marrow by flow cytometry to aid in the diagnosis and differential diagnosis in patients with follicular lymphoma [PDF]

Lu‐Yang Li, Ting Liang, Xiao‐Lan Liu, Xiao‐Lian Wen, Li‐Yuan Qin, Hong‐Wei Zhang, Jing Li, Yu‐Run Du, Jia‐Hui Hou, Rui‐Han Gao, Li-Ping Su, Bao‐feng Yu, Tao Guan   +12 more
openalex   +1 more source

Ultrastructural Organization and Immunohistochemical Analysis of Bcl-2, Caspase 3, and NeuroN Localization in the Spinal Cord of Juvenile Chum Salmon Oncorhynchus keta in Intact Growth and After Traumatic Injury

Evgeniya Vladislavovna Pushchina, Nikita A. Litvinov, Вехова Евгения Евгеньевна   +2 more
openalex   +1 more source

Bcl-2-Dependent Persistence of Mononuclear Phagocytes Promotes Ocular Fibrosis. [PDF]

Int J Mol Sci
Song YS, Wang S, Darjatmoko SR, Sheibani N, Sorenson CM.   +4 more
europepmc   +1 more source

Mentha canadensis leaves induce anti-tumor activity in Ehrlich ascites carcinoma cells through caspase-dependent apoptosis and Bcl-2 interaction

Asma Ul Husna Biswas, Chandan Barai, Tasnima Kamal, Azadur Rahman Bhuiyan, Mahmud Ismail, Zinnat Ara Moni, Abdul Auwal, Nitai Roy, Md Tofazzal Hossain, Md. Shakhawoat Hossain, Farhadul Islam   +10 more
openalex   +1 more source

BCL-2 inhibition at antiretroviral therapy initiation reduces the intact SIV reservoir in macaques. [PDF]

Nat Microbiol
Wiche Salinas TR, Harper J, Deleage C, Nguyen K, Auger J, Flores HR, Kaushik SR, Wilkes AC, Stammen RL, Wood JS, Easley KA, Nelson S, Tharp GK, Bosinger SE, Cottrell ML, Kose E, Immonen TT, Lifson JD, Laird GM, Keele BF, Jones RB, Badley AD, Silvestri G, Kulpa DA, Paiardini M.   +24 more
europepmc   +1 more source