Results 21 to 30 of about 112,671,011 (290)

Deciphering the clinical significance of Beclin-1 and Bcl-2 in urothelial carcinoma of bladder. [PDF]

Indian J Urol
Niharika, Tripathi S, Singhai A, Goel A, Kumar N, Garg M.   +5 more
europepmc   +2 more sources

Extended In Vitro Maturation Reveals a Prolonged Nuclear Maturation Window and Dynamic BAX/BCL-2 Regulation in Dromedary Camel Oocytes. [PDF]

Vet Sci
Alhobish WH, Al-Ghadi MQ, Alyami NM.
europepmc   +2 more sources

Extranodal Organ Involvement in Chronic Lymphocytic Leukemia: Clinical Features and Outcomes With Bruton Tyrosine Kinase and BCL-2 Inhibitors. [PDF]

Cancer Med
Schulze FJ, Shumilov E, Behringer A, Kerkhoff A, Eckhardt M, Bätker S, Maulhardt M, Lenz G, Pohlmann A.   +8 more
europepmc   +3 more sources

Evaluation of Bax and BCL 2 Genes Polymorphisms in Iraqi Women with Breast Cancer [PDF]

Archives of Razi Institute, 2022
The present study aimed to examine the polymorphism -938C > A of BCL-2 gene and promoter -248G>A in the Bax gene, as well as their relationship with specific clinical-pathological characteristics, in patients with breast cancer.
H. F. S Al-Zubaidy, S. R Majeed, D. A. F Al-Koofee   +2 more
doaj   +1 more source

SFTSV exploits PPM1K to inhibit apoptosis through the Bcl-2/BAX/Caspase-3 axis for efficient replication. [PDF]

Virol Sin
Wang Q, Wang B, Liu P, Li Y.
europepmc   +2 more sources

Bcl-B: an “unknown” protein of the Bcl-2 family

Biology Direct, 2023
Bcl-B is a poorly understood protein of the Bcl-2 family that is highly expressed in many healthy tissues and tumor types. Bcl-B is considered an antiapoptotic protein, but many reports have revealed its contradictory roles in different cancer types.
N. V. Pervushin, G. S. Kopeina, B. Zhivotovsky   +2 more
doaj   +1 more source

BCL-2-regulated apoptosis.

, 2023
(A) The BCL-2-regulated apoptotic pathway involves the following proteins pro-survival BCL-2 proteins, pro-apoptotic BH3-only proteins, and apoptosis effectors BAX/BAK proteins. Lines indicate interactions between molecules. (B) In healthy cells, the pro-
Nathaniel Chien (14636956), Hyun Joo (199982), Jennifer Yi (14636950), Shivarni Patel (14636959), Vivian Kellner (14636953), Jerry Tsai (199995), Zaina Chaban (14636962)   +6 more
core   +1 more source

Beyond cell death - antiapoptotic Bcl-2 proteins regulate migration and invasion of colorectal cancer cells in vitro. [PDF]

PLoS ONE, 2013
Migration and invasion of malignant cells are prerequisites for cancer progression and metastasis. The Bcl-2 family of proteins consists of about 25 members and has been extensively studied in the context of apoptosis.
Bruno Christian Koehler, Anna-Lena Scherr, Stephan Lorenz, Toni Urbanik, Nicole Kautz, Christin Elssner, Stefan Welte, Justo Lorenzo Bermejo, Dirk Jäger, Henning Schulze-Bergkamen   +9 more
doaj   +1 more source

Molecular Interactions of Prodiginines with the BH3 Domain of Anti-Apoptotic Bcl-2 Family Members. [PDF]

, 2013
Prodigiosin and obatoclax, members of the prodiginines family, are small molecules with anti-cancer properties that are currently under preclinical and clinical trials. The molecular target(s) of these agents, however, is an open question.
Ali Hosseini (383134), Roberto Quesada (383137), Vanessa Soto-Cerrato, Quesada, Roberto, Guallar, Victor, Hossein, Ali, Victor Guallar (218011), Espona Fiedler, Margarita, Hosseini, Seyed Ali, Vanessa Soto-Cerrato (383136), Guallar Victor, Victor Guallar, Soto-Cerrato Vanessa, Ali Hosseini, Soto Cerrato, Vanessa, Hosseini Ali, Quesada Roberto, Pérez-Tomás Ricardo, Quesada Pato, Roberto, Margarita Espona-Fiedler, Margarita Espona-Fiedler (383135), Pérez Tomás, Ricardo E., Espona-Fiedler Margarita, Ricardo Pérez-Tomás (383138), Ricardo Pérez-Tomás, Pérez Tomás, Ricardo, Roberto Quesada   +26 more
core   +2 more sources

The inhibitory role of stigmasterol on tumor growth by inducing apoptosis in Balb/c mouse with spontaneous breast tumor (SMMT)

BMC Pharmacology and Toxicology, 2022
Background Breast cancer is one of the most common types of cancer in women worldwide. Anti-apoptotic activity of cancer cells is considered the main reason for drug resistance in BC which reduces the 5-year survival rate of patients and is still ...
Mandana AmeliMojarad, Melika AmeliMojarad, Alireza Pourmahdian   +2 more
doaj   +1 more source